Mapping the heart and arteries in coronary artery disease
Myocardial and Arterial Phenotype of Coronary Artery Disease (CAD-MAP): A Multicenter Multimodality Imaging & Physiology Registry
This study is testing new imaging techniques to create a detailed map of the heart and arteries in people with coronary artery disease to see if it can help improve their treatment and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Beijing Anzhen Hospital Academic / other |
| Locations | 2 sites (Beijing, Beijing and 1 other locations) |
| Trial ID | NCT06202300 on ClinicalTrials.gov |
What this trial studies
The CAD-MAP registry aims to create a detailed cardiac imaging map that includes the epicardial coronary artery, coronary microcirculation, and myocardium in patients with coronary artery disease (CAD). By utilizing advanced imaging techniques such as coronary computed tomography angiography, cardiac magnetic resonance, and positron emission tomography/computed tomography, the study seeks to explore the prognostic value of multidimensional imaging biomarkers. This approach intends to enhance risk stratification and optimize treatment outcomes for CAD patients by providing a comprehensive understanding of the underlying pathological mechanisms. The study will include patients who are eligible for coronary angiography and related examinations.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with suspected or confirmed coronary artery disease who can undergo coronary angiography.
Not a fit: Patients with life-threatening conditions such as malignant tumors or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved risk assessment and personalized treatment strategies for patients with coronary artery disease.
How similar studies have performed: Previous imaging cohorts have shown promise in evaluating cardiovascular disease, suggesting that this approach may yield valuable insights, although this specific methodology is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. Age ≥18 years old. * 2. Patients with suspected or confirmed coronary artery disease who are eligible to undergo coronary angiography and IVUS/OCT or functional examination. * 3. Written informed consent. * 4. Subject is willing to comply with all protocol-required follow-up evaluation. Exclusion Criteria: * 1. Malignant tumor, lymphoma, HIV-positive, or cirrhosis with life expectancy \<1 year. * 2. Pregnancy, lactation, or potentially fertile women. * 3. Patients who cannot complete this trial or comply with the protocol.
Where this trial is running
Beijing, Beijing and 1 other locations
- Beijing Anzhen Hospital, Capital Medical University — Beijing, Beijing, China (Recruiting)
- Peking University First Hospital — Beijing, Beijing, China (Recruiting)
Study contacts
- Principal investigator: Xiao Wang, MD — Beijing Anzhen Hospital
- Study coordinator: Xiao Wang, MD
- Email: spaceeye123@126.com
- Phone: 86-10-84005253
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.