Mapping the elasticity of breast masses using ultrasound
Nonlinear Elasticity Mapping of Breast Masses
Mayo Clinic · NCT04863443
This study is testing a new ultrasound technique to see if it can help tell the difference between harmless and cancerous breast lumps by measuring how stretchy they are.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic (other) |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT04863443 on ClinicalTrials.gov |
What this trial studies
This study investigates a novel technique called Nonlinear Elasticity Mapping (NEM) to assess the elasticity of breast masses through ultrasound imaging. By measuring both linear and nonlinear elasticity parameters, the study aims to differentiate between benign and malignant breast masses. The method involves applying varying levels of compression to the breast tissue and analyzing the resulting data to create a detailed map of tissue elasticity. The goal is to validate this technique in a larger patient population to enhance breast cancer diagnosis and management.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with findings on their clinical breast ultrasound who have not undergone mastectomy or have breast implants.
Not a fit: Patients who have a history of mastectomy or breast implants, or those with conditions that prevent proper imaging, will not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could significantly improve the accuracy of breast cancer diagnosis and reduce unnecessary biopsies.
How similar studies have performed: Previous pilot studies have shown promise for this approach, but this study aims to expand the findings to a larger population for more definitive results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Without a history of mastectomy or implants, which are identified to have findings on their clinical breast ultrasound. Exclusion Criteria: * Previous mastectomy or implants * Any condition that does not allow proper use of imaging devices.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Breast Cancer, Breast, Mass