Mapping the AV node and surrounding areas in patients with tachycardia
Official title: Localization of Anatomical Structures Involved in Nodal Tachycardias by High Density Mapping. Feasibility Study.
Run by University Hospital, Toulouse · NCT05296954 · Data updated 2026-11-12
This study is testing a new mapping technique to see if it can help doctors locate the AV node and nearby pathways better in patients with a specific type of fast heart rate called AVNRT.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Status | Recruiting |
| Started | February 4, 2022 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | June 1, 2026 |
| Trial ID | NCT05296954 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients without heart disease who present with AVNRT and control subjects without nodal tachycardia undergoing other ablation procedures.
✕Probably not a fit
Patients with underlying structural heart disease or a history of atrial ablation or atrial tachycardia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to utilize high-resolution mapping systems to accurately locate the atrioventricular (AV) node and nearby slow-conducting pathways in patients with atrioventricular nodal reentry tachycardia (AVNRT). It will involve two groups: one consisting of patients undergoing AVNRT ablation and another group of control patients without nodal tachycardia. The study will employ the RHYTHMIA HDx 3D electro-anatomical mapping system and the multipolar ORION catheter to gather detailed mapping data. The findings will be compared to conventional fluoroscopy ablation areas to assess the effectiveness of the mapping techniques.
Why it matters
Potential benefit: If successful, this study could enhance the precision of ablation procedures for patients with tachycardia, potentially leading to better outcomes and reduced recurrence rates.
How similar studies have gone: Other studies utilizing high-resolution mapping techniques have shown promise in improving the accuracy of cardiac ablation procedures, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Group 1: Patients without heart disease presenting with reciprocal tachycardia by intra-nodal reentry. Group 2: Control subjects, without nodal tachycardia, without heart disease, and admitted for ablation of atrial fibrillation or ventricular extrasystoles on a healthy heart and with a 3D system. Exclusion Criteria: * Presence of underlying structural heart disease or history of atrial ablation or atrial tachycardia * Minor or protected patient * Patient under guardianship, curatorship or safeguard of justice
Where it's running
-
CHU de Toulouse
Toulouse, France Recruiting
Study contacts
- Principal investigator: Philippe MAURY, MD — University Hospital, Toulouse
- Study coordinator: Philippe MAURY, MD
- Email: maury.p@chu-toulouse.fr
- Phone: 5 61 32 33 16
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.