Mapping the AV node and surrounding areas in patients with tachycardia
Localization of Anatomical Structures Involved in Nodal Tachycardias by High Density Mapping. Feasibility Study.
This study is testing a new mapping technique to see if it can help doctors locate the AV node and nearby pathways better in patients with a specific type of fast heart rate called AVNRT.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Trial ID | NCT05296954 on ClinicalTrials.gov |
What this trial studies
This study aims to utilize high-resolution mapping systems to accurately locate the atrioventricular (AV) node and nearby slow-conducting pathways in patients with atrioventricular nodal reentry tachycardia (AVNRT). It will involve two groups: one consisting of patients undergoing AVNRT ablation and another group of control patients without nodal tachycardia. The study will employ the RHYTHMIA HDx 3D electro-anatomical mapping system and the multipolar ORION catheter to gather detailed mapping data. The findings will be compared to conventional fluoroscopy ablation areas to assess the effectiveness of the mapping techniques.
Who should consider this trial
Good fit: Ideal candidates include patients without heart disease who present with AVNRT and control subjects without nodal tachycardia undergoing other ablation procedures.
Not a fit: Patients with underlying structural heart disease or a history of atrial ablation or atrial tachycardia may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the precision of ablation procedures for patients with tachycardia, potentially leading to better outcomes and reduced recurrence rates.
How similar studies have performed: Other studies utilizing high-resolution mapping techniques have shown promise in improving the accuracy of cardiac ablation procedures, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Group 1: Patients without heart disease presenting with reciprocal tachycardia by intra-nodal reentry. Group 2: Control subjects, without nodal tachycardia, without heart disease, and admitted for ablation of atrial fibrillation or ventricular extrasystoles on a healthy heart and with a 3D system. Exclusion Criteria: * Presence of underlying structural heart disease or history of atrial ablation or atrial tachycardia * Minor or protected patient * Patient under guardianship, curatorship or safeguard of justice
Where this trial is running
Toulouse
- CHU de Toulouse — Toulouse, France (Recruiting)
Study contacts
- Principal investigator: Philippe MAURY, MD — University Hospital, Toulouse
- Study coordinator: Philippe MAURY, MD
- Email: maury.p@chu-toulouse.fr
- Phone: 5 61 32 33 16
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.