Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Mapping lymph nodes in colon cancer using fluorescent dye

Official title: Lymph Node Mapping Via the Flourescent Dye ICG in Colon Cancer Through Preoperative Application

Run by Universitätsklinikum Hamburg-Eppendorf · NCT04959604 · Data updated 2026-11-12

This study is testing if a special dye can help doctors see lymph nodes during colon cancer surgery to improve how they remove cancer and help patients do better afterward.

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment30 (estimated)
SponsorUniversitätsklinikum Hamburg-Eppendorf
Academic / other
Locations1 site (Hamburg)
StatusRecruiting
StartedMay 31, 2021
Main results expectedDecember 31, 2025
Study endsDecember 30, 2026
Registry record updatedMay 23, 2023
Trial IDNCT04959604 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals with histologically diagnosed adenocarcinoma of the ascending, transverse, descending, or sigmoid colon.

Probably not a fit

Patients with other types of carcinoma or those for whom endoscopic marking is not possible may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of using indocyanine green (ICG) dye to visualize lymph nodes draining from colon carcinoma during surgery. Participants diagnosed with adenocarcinoma of the colon will receive ICG injections prior to surgery, allowing for the identification of lymph nodes that may be outside the standard resection lines. The study aims to document the locations of these nodes and correlate their fluorescence with cancer positivity. This approach could enhance surgical precision and potentially improve patient outcomes.

Why it matters

Potential benefit: If successful, this method could lead to more comprehensive cancer resections and better management of lymph node metastases in colon cancer patients.

How similar studies have gone: Similar studies using fluorescent dyes for lymphatic mapping have shown promising results, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* histologically diagnosed carcinoma of the ascending, transverse, descending or sigmoid colon.

Exclusion Criteria:

* not wanting to participate
* other carcinoma then adenocarcinoma
* endoscopic marking not possible

Where it's running

  • University of Hamburg Medical Institutions
    Hamburg, Germany
    Recruiting

Study contacts

  • Principal investigator: Daniel Perez, Prof. Dr. — Dept of General Visceral and Thoracic Surgery
  • Study coordinator: Katharina L Lucas, MD
  • Email: katharina.lucas@uni-wh.de
  • Phone: +4915779600815

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.