Mapping lymph nodes in colon cancer using fluorescent dye
Official title: Lymph Node Mapping Via the Flourescent Dye ICG in Colon Cancer Through Preoperative Application
Run by Universitätsklinikum Hamburg-Eppendorf · NCT04959604 · Data updated 2026-11-12
This study is testing if a special dye can help doctors see lymph nodes during colon cancer surgery to improve how they remove cancer and help patients do better afterward.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg) |
| Status | Recruiting |
| Started | May 31, 2021 |
| Main results expected | December 31, 2025 |
| Study ends | December 30, 2026 |
| Registry record updated | May 23, 2023 |
| Trial ID | NCT04959604 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with histologically diagnosed adenocarcinoma of the ascending, transverse, descending, or sigmoid colon.
✕Probably not a fit
Patients with other types of carcinoma or those for whom endoscopic marking is not possible may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of using indocyanine green (ICG) dye to visualize lymph nodes draining from colon carcinoma during surgery. Participants diagnosed with adenocarcinoma of the colon will receive ICG injections prior to surgery, allowing for the identification of lymph nodes that may be outside the standard resection lines. The study aims to document the locations of these nodes and correlate their fluorescence with cancer positivity. This approach could enhance surgical precision and potentially improve patient outcomes.
Why it matters
Potential benefit: If successful, this method could lead to more comprehensive cancer resections and better management of lymph node metastases in colon cancer patients.
How similar studies have gone: Similar studies using fluorescent dyes for lymphatic mapping have shown promising results, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * histologically diagnosed carcinoma of the ascending, transverse, descending or sigmoid colon. Exclusion Criteria: * not wanting to participate * other carcinoma then adenocarcinoma * endoscopic marking not possible
Where it's running
-
University of Hamburg Medical Institutions
Hamburg, Germany Recruiting
Study contacts
- Principal investigator: Daniel Perez, Prof. Dr. — Dept of General Visceral and Thoracic Surgery
- Study coordinator: Katharina L Lucas, MD
- Email: katharina.lucas@uni-wh.de
- Phone: +4915779600815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.