Mapping heart rhythms in patients with atrial fibrillation before their first procedure

Observational Study of Sinus Rhythm Mapping in Pulmonary Vein Isolation Naive Patients With Atrial Fibrillation

Observational Ziekenhuis Oost-Limburg · NCT06098664

This study is testing a new AI tool that looks at heart scans to see if it can help predict problems for people with atrial fibrillation before they have their first heart procedure.

Quick facts

Study typeObservational
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorZiekenhuis Oost-Limburg Academic / other
Locations1 site (Genk, Limburg)
Trial IDNCT06098664 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the effectiveness of an artificial intelligence-enabled ECG algorithm in predicting electropathology in patients with atrial fibrillation (AF) who are undergoing their first pulmonary vein isolation (PVI) procedure. The study focuses on patients who have a 12-lead ECG available in sinus rhythm within the last 14 days. By analyzing the electrical properties of the heart, the researchers hope to identify potential complications and improve treatment outcomes for AF patients. The study will utilize advanced deep neural network technology to assess the data collected from the ECG.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are experiencing their first PVI procedure for atrial fibrillation.

Not a fit: Patients with severe mitral insufficiency or those participating in other conflicting studies may not benefit from this research.

Why it matters

Potential benefit: If successful, this study could enhance the ability to predict complications in atrial fibrillation patients undergoing PVI, leading to better treatment strategies.

How similar studies have performed: While the use of AI in ECG analysis is a growing field, this specific approach to predicting electropathology in AF patients is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Provide signed and dated informed consent.
* First PVI-procedure
* Age is 18 years or higher.
* 12-lead ECG available in SR during the last 14 days.

Exclusion Criteria:

* Mitral insufficiency of grade 3 or 4.
* Participating in another study that may interfere with participation in this study

Where this trial is running

Genk, Limburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial FibrillationArtificial IntelligenceDeep Neural NetworkElectrocardiogramPulmonary Vein Isolation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.