Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Mapping chest wall perforators for partial breast reconstruction

Official title: Anatomical Landmarks for Chest Wall Perforators Used for Partial Breast Reconstruction (LaPBrecon)

Run by University Hospitals of North Midlands NHS Trust · NCT07006662 · Data updated 2026-11-12

This study tests how chest wall perforator locations relate to body landmarks in women undergoing breast-conserving surgery to help guide perforator flaps for reconstruction.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment20 (estimated)
SponsorUniversity Hospitals of North Midlands NHS Trust
Academic / other
Locations1 site (Stoke-on-Trent)
StatusRecruiting
StartedAugust 4, 2026
Main results expectedDecember 1, 2027
Study endsDecember 1, 2027
Registry record updatedSeptember 9, 2026
Trial IDNCT07006662 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women aged 18 or older undergoing elective breast surgery with BMI ≤ 30 kg/m2, who are willing to consent and comply with study procedures.

Probably not a fit

Patients who do not undergo perforator-based reconstruction or whose anatomy does not rely on the studied perforators may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This 6-month proof-of-concept study aims to map chest wall perforators used in partial breast reconstruction to nearby anatomical landmarks. Eligible participants are women undergoing elective breast surgery with BMI ≤ 30 kg/m2 who will have a 30-minute assessment using a hand-held Doppler to identify perforators and relate their positions to soft tissue and bony landmarks. Data will be analyzed to identify common anatomical locations for thoracodorsal, lateral thoracic, and intercostal perforators to potentially streamline intraoperative localization. The study focuses on improving cosmetic outcomes after breast-conserving procedures by clarifying perforator anatomy. No interventions are described beyond the mapping assessment.

Why it matters

Potential benefit: If successful, the findings could help surgeons quickly locate reliable perforators during reconstruction, potentially improving cosmetic results and reducing operative time.

How similar studies have gone: Previous cadaveric and intraoperative work informed perforator anatomy, but this study adds live, patient-specific landmark mapping to guide practice.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing elective breast surgery
* Age ≥ 18 years
* Female
* BMI ≤ 30 kg/m2
* Willing and able to give fully informed consent,
* Willing and able to comply with the study procedures

Exclusion Criteria:

* Pregnant patients
* Previous bilateral Breast or axillary surgery
* Undergoing bilateral oncoplastic procedure or requiring bilateral pre-operative marking
* Undergoing breast surgery requiring pre-operative marking of some of the landmarks and has had contralateral breast or axillary surgery in the past
* Surgery planned within 24 hours of screening for eligibility
* Known history of allergy or contact dermatitis to ultrasound gels

Where it's running

  • University Hospitals of North Midlands NHS Trust
    Stoke-on-Trent, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.