Mapping autonomic and enteric functions in patients with obesity
Official title: Adrenergic Cholinergic Enteric Measures/Mapping
Run by University of Louisville · NCT04013282 · Data updated 2026-11-12
This study looks at how different body functions relate to obesity by comparing patients' stomach emptying times and other health measures to see if there’s a connection.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 10 Years to 80 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | University of Louisville Academic / other |
| Locations | 1 site (Louisville, Kentucky) |
| Status | Recruiting |
| Started | October 1, 2012 |
| Main results expected | October 1, 2025 |
| Study ends | October 1, 2025 |
| Registry record updated | January 10, 2025 |
| Trial ID | NCT04013282 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients exhibiting symptoms suggestive of autonomic and/or enteric disorders.
✕Probably not a fit
Patients with anatomic obstructions of the GI tract, pregnancy, or psychiatric disorders that hinder assessment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines patients who underwent autonomic and enteric profiling at the University of Louisville between 2012 and 2019. It records the results of these physiologic measures and compares them to standardized gastric emptying values as the primary outcome. Additionally, the study evaluates metabolic measures such as weight and BMI, as well as gastrointestinal symptoms reported by patients. The goal is to better understand the relationship between these measures and obesity.
Why it matters
Potential benefit: If successful, this study could provide insights into the physiological mechanisms underlying obesity, potentially leading to improved treatment strategies.
How similar studies have gone: While this approach is observational and builds on existing profiling techniques, similar studies have shown promise in understanding the autonomic and enteric contributions to obesity.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with the symptoms suggestive of autonomic and/or enteric disorders. Exclusion Criteria: * Anatomic obstruction of the GI tract * Pregnancy * Inability of patient or guardian to sign informed consent, if needed * Psychiatric disorders precluding assessment and treatment of the patient's GI condition.
Where it's running
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University of Louisville
Louisville, Kentucky, United States Recruiting
Study contacts
- Principal investigator: Thomas Abell — University of Louisville
- Study coordinator: Thomas L Abell
- Email: thomas.abell@louisville.edu
- Phone: (502)852-6991
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.