Manual versus automated heart strain measurement during cardiac surgery
Automated Measurements of Left Ventricular Longitudinal Strain: Are the Results Comparable to Manual Measurements During Cardiac Surgery?
This test tries to see if fully automated strain analysis of transesophageal echocardiography can give reliable, fast measurements of left ventricular function for adults having cardiac surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Trial ID | NCT07496424 on ClinicalTrials.gov |
What this trial studies
This observational study compares conventional manual myocardial strain analysis with fully automated strain software performed on transesophageal echocardiography (TEE) images during adult cardiac surgery. Analyses are done using GE Vivid systems (S60, S70, E95) with EchoPAC and TOMTEC software to directly compare time required and agreement between methods. The study enrolls adult cardiac surgery patients in sinus rhythm without severe valvular regurgitation and excludes cases with poor image quality or mechanical circulatory support. The goal is to determine whether automated strain provides reliable intraoperative measurements fast enough to be clinically useful.
Who should consider this trial
Good fit: Ideal candidates are adults (≥18 years) undergoing cardiac surgery who are in sinus rhythm, have no severe valvular regurgitation, and can be imaged with the specified GE echocardiography systems and software.
Not a fit: Patients with inadequate TEE image quality, any severe valvular regurgitation, mechanical circulatory support (e.g., LVAD, Impella, ECMO), or non‑sinus rhythms are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, clinicians could obtain reliable left ventricular strain measurements within seconds during surgery, enabling earlier risk detection and more timely, targeted treatment.
How similar studies have performed: Automated strain tools have shown promise in transthoracic and offline analyses, but their reliability for intraoperative TEE applications is less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult (≥18 years) cardiac surgery patients * Sinus rhythm * No severe valvular regurgitation * Use of General Electric (GE) echocardiography systems (Vivid S60, S70, E95) and corresponding EchoPAC software as well as TOMTEC software. Exclusion Criteria: * Inadequate image quality * Any severe heart valve regurgitation * Mechanical circulatory support systems (e.g., LVAD, Impella, ECMO)
Where this trial is running
Vienna
- General Hospital of Vienna - Medical University of Vienna — Vienna, Austria (Recruiting)
Study contacts
- Study coordinator: Bruno Mora, Dr, MD, PhD
- Email: bruno.mora@meduniwien.ac.at
- Phone: +4314040041090
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.