Manual manipulation after frenotomy for infants with tongue tie

Effectiveness of Post-Procedural Manual Manipulation for Infant Ankyloglossia in Enhancing Breastfeeding and Reducing Revision Rates: A Prospective Randomized Trial

Not applicable Interventional Georgetown University · NCT06830148

This study is testing if tongue stretching and suck re-training exercises after a tongue tie surgery can help infants breastfeed better and prevent the tongue tie from coming back.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment110 (estimated)
AgesN/A to 90 Days
SexAll
SponsorGeorgetown University Academic / other
Locations1 site (Washington D.C., District of Columbia)
Trial IDNCT06830148 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of post-frenotomy manual manipulation in infants diagnosed with ankyloglossia. Infants undergoing frenotomy will be randomly assigned to either an intervention group, which will perform tongue stretching and suck re-training exercises, or a control group with no intervention. The study will assess the impact of these exercises on the rates of frenulum regrowth and breastfeeding outcomes. Follow-up assessments will be conducted to monitor adherence and any complications.

Who should consider this trial

Good fit: Ideal candidates are infants under 90 days old with ankyloglossia who are exclusively or partially breastfed.

Not a fit: Patients who are older than 90 days, exclusively bottle-fed, or have undergone previous frenotomy procedures may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve breastfeeding outcomes for infants with ankyloglossia.

How similar studies have performed: While similar approaches have been explored, this specific intervention's effectiveness remains to be fully validated.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* infants less than 90 days old with ankyloglossia who undergo outpatient frenotomy using cold-steel scissors and will be exclusively or partially breastfed.

Exclusion Criteria:

* infants older than 90 days, those who will be exclusively bottle fed, infants who undergo concomitant lip tie release, those who undergo laser frenotomy, and infants who have previously undergone a frenotomy.
* infants with a gestational age of less than 36 weeks, those in the NICU or post-partum unit, infants who didn't receive the vitamin K injection, and those with congenital anomalies or medical conditions affecting breastfeeding

Where this trial is running

Washington D.C., District of Columbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnkyloglossiaBreastfeeding Supporttongue tiebreastfeedingexercisesinfantpediatric otolaryngologyfrenotomy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.