Mandala painting to reduce anxiety and nausea during chemotherapy

The Effect of Mandala Painting During Chemotherapy on Anxiety, Nausea, and Comfort Levels

Not applicable Interventional Uludag University · NCT07269340

This trial will try mandala coloring during chemotherapy to see if it reduces anxiety and nausea and improves comfort for adults starting their first chemotherapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorUludag University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Bursa)
Trial IDNCT07269340 on ClinicalTrials.gov

What this trial studies

Participants who are adults receiving their first course of chemotherapy will be asked to do mandala painting during infusion sessions as a non-pharmacological distraction. The study measures patient-reported anxiety, nausea, and comfort using standard instruments (including the STAI) and compares outcomes with usual care. People with psychiatric or neurological diagnoses, dementia, low education level, prior chemotherapy, or planned concurrent radiotherapy are excluded. The intervention is delivered on-site during chemotherapy at Uludağ University in Bursa.

Who should consider this trial

Good fit: Adults over 18 starting their first chemotherapy who can read at least a secondary-school level and do not have psychiatric, neurological, or cognitive disorders or planned concurrent radiotherapy are ideal candidates.

Not a fit: Patients with dementia, active psychiatric or neurological illness, insufficient reading ability, prior chemotherapy exposure, planned radiotherapy, or physical limitations preventing painting may not receive benefit.

Why it matters

Potential benefit: If successful, this simple, low-cost activity could lessen anxiety and nausea and make chemotherapy sessions more comfortable without adding medications.

How similar studies have performed: Small prior studies in cancer patients have suggested mandala coloring can reduce distress and improve psychological well-being, but no prior study has comprehensively targeted anxiety, nausea, and comfort specifically during chemotherapy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \> 18 years old,
* Receiving chemotherapy for the first time

Exclusion Criteria:

* Have a lower education level than secondary school (The STAI is appropriate for those who have at least a sixth-grade reading level),
* Diagnosed with psychiatric and neurological diseases,
* Diagnosed with dementia,
* Received chemotherapy treatment more than once,
* Planned to receive radiotherapy treatment together with chemotherapy.

Where this trial is running

Bursa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mandala PaintingChemotherapyVomitingAnxietyComfortNursing Care
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.