Mandala coloring to ease anxiety and discomfort during chemotherapy

The Effect of Mandala Coloring on Psychological Distress, Anxiety, and Comfort in Breast Cancer Patients Receiving Outpatient Chemotherapy

Not applicable Interventional Artvin Coruh University · NCT07367269

This trial will test whether 30 minutes of mandala coloring during outpatient chemotherapy can reduce anxiety and distress and improve comfort for adults with breast cancer.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorArtvin Coruh University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Artvin)
Trial IDNCT07367269 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial will enroll 60 breast cancer patients receiving outpatient chemotherapy at Artvin State Hospital and randomly assign them 1:1 to mandala coloring or routine care. Participants in the intervention group will color mandala patterns for 30 minutes at the start of their chemotherapy session while controls receive routine care only. Psychological distress, anxiety, and comfort will be measured immediately before and after the chemotherapy session. Block randomization with allocation concealment using sequentially numbered opaque sealed envelopes will be used to reduce bias.

Who should consider this trial

Good fit: Adults (≥18) with a diagnosis of breast cancer receiving outpatient chemotherapy who can communicate, have no physical limitation to coloring, and are willing to participate.

Not a fit: Patients with severe cognitive impairment, hand or arm disabilities that prevent coloring, inpatient chemotherapy, or those unwilling to participate may not receive benefit.

Why it matters

Potential benefit: If successful, this low-cost activity could help reduce anxiety and distress and increase comfort during chemotherapy sessions.

How similar studies have performed: Prior small studies and complementary-medicine reports suggest mandala coloring can reduce anxiety and distress in cancer patients, but evidence specifically during outpatient chemotherapy is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being 18 years of age or older
* Having a diagnosis of breast cancer and receiving chemotherapy
* Having no communication problems
* Having no physical disability that would prevent mandala coloring
* Being willing to participate in the study

Exclusion Criteria:

* not meeting inclusion criteria

Where this trial is running

Artvin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.