Managing stress to improve biological age in breast cancer patients

Psychological and Biological Outcomes in Breast Cancer Patients After Pythagorean Self-Awareness Intervention.

NA · National and Kapodistrian University of Athens · NCT05984914

This study is testing whether a stress management program can help breast cancer survivors feel better and possibly slow down their biological aging.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 70 Years
SexFemale
SponsorNational and Kapodistrian University of Athens (other)
Drugs / interventionschemotherapy
Locations1 site (Athens)
Trial IDNCT05984914 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of a stress management program, specifically the Pythagorean Self-Awareness Intervention, on telomere length in T-leukocytes of breast cancer patients who have completed their cancer treatments, except for hormonal therapy. Participants will complete self-referred questionnaires, provide hair cortisol samples, and undergo blood material extraction to assess the impact of stress on their biological age. The goal is to understand how managing stress can influence cellular aging and potentially improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are women diagnosed with primary breast cancer who have completed all anticancer therapies except hormonal therapy.

Not a fit: Patients with psychiatric diagnoses, metastasis, or those who have previously participated in stress management studies may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the quality of life and survival rates for breast cancer patients by mitigating the effects of stress.

How similar studies have performed: Previous studies have indicated a correlation between stress management and improved health outcomes, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of primary breast cancer
* Completion of anticancer therapy (except for hormonal therapy)

Exclusion Criteria:

* Psychiatric diagnosis and treatment
* Metastasis
* Previous participation in any stress management and health promotion study
* Inability to read or write in Greek

Where this trial is running

Athens

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stress, Breast Cancer, Telomere Length, Mean Leukocyte, Lifestyle, Stress management, Telomeres, Biological age, PSAI

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.