Managing pain after wisdom tooth removal with advanced platelet-rich fibrin
Assessment of Chronic Pain Predictors Following Surgical Removal of Mandibular Third Molars
EARLY_PHASE1 · Aalborg University Hospital · NCT06377839
This study is testing if a special treatment using advanced platelet-rich fibrin can help reduce pain for adults after having their wisdom teeth taken out.
Quick facts
| Phase | EARLY_PHASE1 |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aalborg University Hospital (other) |
| Locations | 1 site (Aalborg, Nordjylland) |
| Trial ID | NCT06377839 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of advanced platelet-rich fibrin in reducing pain following the surgical removal of impacted mandibular third molars. It aims to identify specific risk factors and predictors for the development of chronic pain after surgery. The research will involve patients aged 18 and older who require the extraction of their wisdom teeth, and it will assess the intensity and duration of acute postoperative pain. The study seeks to improve patient outcomes by potentially minimizing the transition from acute to chronic pain.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with semi- or fully impacted mandibular third molars requiring surgical removal.
Not a fit: Patients with chronic pain syndromes, those requiring daily analgesics, pregnant individuals, or those with psychiatric issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery for patients undergoing wisdom tooth extraction.
How similar studies have performed: While the use of platelet-rich fibrin in surgical procedures has shown promise in other contexts, this specific application for wisdom tooth extraction is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * Presence of a semi- or fully impacted mandibular third molar. * Indication for surgical removal of mandibular third molar. Exclusion Criteria: * Patients suffering from chronic pain syndrome. * Patients in need of daily analgetic. * Pregnancy. * Psychiatric problems or unrealistic expectations.
Where this trial is running
Aalborg, Nordjylland
- Department of Oral and Maxillofacial surgery, Aalborg University Hospital — Aalborg, Nordjylland, Denmark (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pain Syndrome, Pain, surgery, quality of life,