Managing pain after lumbar spine surgery

Perioperative Analgesic Manipulations to Mitigate Pain After Elective Lumbar Spinal Surgeries: A Prospective Case-controlled Study

Not applicable Interventional Benha University · NCT06662318

This study is testing a new way to manage pain after back surgery by using a mix of different medications to help patients feel better and recover faster without relying too much on opioids.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment75 (estimated)
Ages25 Years to 75 Years
SexAll
SponsorBenha University Academic / other
Locations1 site (Banhā, El Qalyoubia)
Trial IDNCT06662318 on ClinicalTrials.gov

What this trial studies

This study focuses on improving pain management for patients undergoing elective lumbar spine surgery by utilizing a multimodal analgesic approach. It aims to reduce reliance on opioids by combining non-opioid medications such as fentanyl citrate, dexmedetomidine, and lidocaine hydrochloride. The goal is to enhance recovery and minimize the risk of chronic pain associated with postoperative discomfort. By tailoring pain management strategies to individual patients, the study seeks to optimize outcomes and improve overall patient satisfaction.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for lumbar discectomy who do not have any exclusion criteria.

Not a fit: Patients with obesity grade ≥II, opioid dependence, or uncontrolled medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to better pain control and faster recovery for patients after lumbar spine surgery.

How similar studies have performed: Other studies have shown promise in using multimodal analgesic approaches for postoperative pain management, indicating potential success for this method.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who had LDD and required lumbar discectomy,
* Patients are free of exclusion criteria and accepted to participate in the study.

Exclusion Criteria:

* The presence of other indications for spinal surgery;
* Obesity of grade ≥II;
* Patients of ASA grade \>II;
* opioid dependence for preoperative pain;
* The presence of other causes of preoperative pain;
* The presence of preoperative psychiatric manifestations especially delirium and/or cognitive dysfunction;
* The presence of contraindications for the use of the study drugs;
* The presence of uncontrolled cardiac, renal, or hepatic disorders and essential hypertension.

Where this trial is running

Banhā, El Qalyoubia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pain, Postoperative
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.