Managing morbidly adherent placenta with conservative measures

Beni-Suef University Hospital Simplified Conservative Approach for Managing Placenta Accreta Spectrum: RCT

Not applicable Interventional Beni-Suef University · NCT06465836

This study is testing new ways to manage a serious pregnancy condition called placenta accreta without having to remove the uterus, so women can keep their fertility and avoid complications.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment172 (estimated)
Ages25 Years to 45 Years
SexFemale
SponsorBeni-Suef University Academic / other
Locations1 site (Cairo)
Trial IDNCT06465836 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of modified uterine artery ligation and myometrial compression as conservative measures for managing morbidly adherent placenta, specifically placenta accreta. The approach aims to avoid hysterectomy, which is often the standard treatment, in order to preserve fertility and minimize complications associated with surgical removal of the placenta. The study follows guidelines from the International Federation of Gynecology and Obstetrics (FIGO) and focuses on techniques that prevent excessive bleeding while maintaining the integrity of the placenta.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women over 28 weeks gestation with confirmed placenta previa and stable clinical conditions.

Not a fit: Patients experiencing significant vaginal bleeding or those with underlying medical disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could allow patients to preserve their fertility while effectively managing the risks associated with placenta accreta.

How similar studies have performed: While conservative management approaches have been explored, this specific methodology is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Gestational age more than 28 weeks as determined by LMP and ultrasound.
* Placenta previa as confirmed by ultrasound.
* Clinically stable with no or mild vaginal bleeding.
* No evidence of fetal compromise.
* Patient consent.

Exclusion Criteria:

* Vaginal bleeding
* Medical disorders

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Placenta Accreta
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.