Managing hypertension with community health workers in rural Guatemala

Assessing the Efficacy and Safety of Community Health Worker-led Hypertension Management Enabled by a Mobile Clinical Decision Support Application Compared to Physician Care: a Randomized, Controlled, Noninferiority Trial

Not applicable Interventional University of Wisconsin, Madison · NCT06444308

This study is testing if community health workers using a mobile app can help people in rural Guatemala manage their high blood pressure better than regular doctor visits.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment460 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Wisconsin, Madison Academic / other
Locations1 site (San Lucas Tolimán)
Trial IDNCT06444308 on ClinicalTrials.gov

What this trial studies

This study evaluates whether community health workers (CHWs), supported by a mobile health application and remote physician supervision, can effectively manage hypertension compared to traditional physician-led care. The innovative care model utilizes a mobile application that provides clinical decision support based on established protocols for hypertension management. The study will take place over 12-24 months in rural Guatemala, focusing on improving systolic blood pressure in patients diagnosed with hypertension. The research aims to assess not only the effectiveness of this approach but also its safety, patient acceptability, and cost-effectiveness.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a diagnosis of hypertension and a blood pressure of 140/90 or higher, or those currently on antihypertensive medication.

Not a fit: Patients who are pregnant or have severe comorbid conditions with a life expectancy of less than one year may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide accessible and effective hypertension management in underserved rural populations.

How similar studies have performed: Previous studies utilizing community health workers for chronic disease management have shown success, indicating potential for this approach in hypertension management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults age 18 or greater with diagnosis of hypertension AND blood pressure (BP) greater than or equal to 140/90 OR currently taking antihypertensive medication.
* Ability to provide informed consent

Exclusion Criteria:

* Pregnancy
* Severe comorbid condition(s) with life expectancy less than 1 year

Where this trial is running

San Lucas Tolimán

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertensioncommunity health worker
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.