Management of patients eligible for CAR-T cell therapy
Official title: Evaluation of the Real-life Management of Patients Eligible for CAR-T Cell Therapy for Hematologic Malignancies at Toulouse University Hospital
Run by University Hospital, Toulouse · NCT06369389 · Data updated 2026-11-12
This study looks at how patients eligible for CAR-T cell therapy are managed in real life to better understand their needs and care over five years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 550 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Drugs / interventions | CAR-T, immunotherapy |
| Locations | 1 site (Toulouse, CHU de Toulouse) |
| Status | Recruiting |
| Started | April 30, 2024 |
| Main results expected | December 31, 2033 |
| Study ends | December 31, 2034 |
| Registry record updated | April 10, 2025 |
| Trial ID | NCT06369389 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients eligible for CAR-T treatment for hemopathy at Toulouse University Hospital between 2019 and 2028.
✕Probably not a fit
Patients who are under guardianship or object to data collection may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the real-life management of patients eligible for CAR-T cell therapy for hemopathy at Toulouse University Hospital. It aims to collect data over a five-year period to evaluate patient-centered indicators and care pathways, addressing the growing needs associated with the increasing number of CAR-T cell indications. The study is part of the French national DESCAR-T registry, which serves as a reference for evaluating the post-authorization use of CAR-T treatments.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of CAR-T cell therapy's effectiveness and improve patient care pathways.
How similar studies have gone: Other studies have shown success in evaluating CAR-T therapies, but this specific approach to real-life data collection is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient eligible for CAR-T treatment for hemopathy at TOULOUSE University Hospital under early access or marketing authorization or as part of a clinical trial between 01/01/2019 and 31/12/2028 * Patient able to understand the purpose and constraints of the research project * Patient has read the study information leaflet and does not object to the research. Exclusion Criteria: * Patient under guardianship, curatorship or safeguard of justice * Patient objects to the collection of data concerning him/her
Where it's running
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CHU de Toulouse
Toulouse, CHU de Toulouse, France Recruiting
Study contacts
- Principal investigator: Pierre BORIES, MD — University Hospital, Toulouse
- Study coordinator: Pierre BORIES, MD
- Email: bories.pierre@iuct-oncopole.fr
- Phone: 0531156415
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This study is testing if a combination of golcadomide and rituximab can help patients with aggressive B-cell lymphoma get ready for CAR T-cell therapy.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.