Management of knee osteoarthritis with surgery
Evaluation of the Results of High Tibial Osteotomy with or Without Lateral Patellar Facetectomy in Treatment of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis; a Comparative Study
This study is testing whether a specific knee surgery can help people with arthritis in their knee feel better and move more easily.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 35 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Trial ID | NCT06762171 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of open wedge high tibial osteotomy (OWHTO) in patients with combined patellofemoral and medial compartment knee osteoarthritis. Participants will be randomly assigned to receive either OWHTO with or without arthroscopic partial lateral patellar facetectomy. The surgical procedure involves a thorough examination of the knee joint and potential treatment of any concurrent pathologies. The aim is to assess the outcomes of these surgical interventions in improving knee function and alleviating pain.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 35-60 with mild to moderate knee osteoarthritis and specific anatomical criteria.
Not a fit: Patients with advanced osteoarthritis requiring total knee replacement or those with significant deformities or inflammatory diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain relief and functional outcomes for patients with knee osteoarthritis.
How similar studies have performed: Other studies have shown promising results with similar surgical approaches, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 35-60years 2. Mild to moderate TFOA (G I-II-III) Kellgren-Lawrence (KL) scale (16) 3. Anterior knee pain (PFOA) 4. No involvement of the lateral compartment 5. range of motion of at least 120° flexion 6. Body mass index (BMI) \<30kg/m2 7. varus angle degree \<10° Exclusion Criteria: 1. advanced case of TFOA (G VI KL scale), which requires total knee replacement. 2. flexion deformity ≥15° 3. inflammatory disease (such as rheumatoid arthritis).
Where this trial is running
Sohag, Sohag Governorate
- Faculty of medicine, Sohag university — Sohag, Sohag Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Ahmed Tarek Ahmed, Assistant lecturer
- Email: Ahmed.Tarek@med.sohag.edu.eg
- Phone: 01033667677
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.