Clinical trial Recruiting at 1 site Interventional Ages 35 to 60

Management of knee osteoarthritis with surgery

Official title: Evaluation of the Results of High Tibial Osteotomy with or Without Lateral Patellar Facetectomy in Treatment of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis; a Comparative Study

Run by Sohag University · NCT06762171 · Data updated 2026-11-12

This study is testing whether a specific knee surgery can help people with arthritis in their knee feel better and move more easily.

Quick facts

Study typeInterventional
Ages35 Years to 60 Years
SexAll
Enrollment40 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag, Sohag Governorate)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedJune 2025
Study endsNovember 2026
Registry record updatedJanuary 7, 2025
Trial IDNCT06762171 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 35-60 with mild to moderate knee osteoarthritis and specific anatomical criteria.

Probably not a fit

Patients with advanced osteoarthritis requiring total knee replacement or those with significant deformities or inflammatory diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of open wedge high tibial osteotomy (OWHTO) in patients with combined patellofemoral and medial compartment knee osteoarthritis. Participants will be randomly assigned to receive either OWHTO with or without arthroscopic partial lateral patellar facetectomy. The surgical procedure involves a thorough examination of the knee joint and potential treatment of any concurrent pathologies. The aim is to assess the outcomes of these surgical interventions in improving knee function and alleviating pain.

Why it matters

Potential benefit: If successful, this approach could significantly improve pain relief and functional outcomes for patients with knee osteoarthritis.

How similar studies have gone: Other studies have shown promising results with similar surgical approaches, indicating potential for success in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 35-60years
2. Mild to moderate TFOA (G I-II-III) Kellgren-Lawrence (KL) scale (16)
3. Anterior knee pain (PFOA)
4. No involvement of the lateral compartment
5. range of motion of at least 120° flexion
6. Body mass index (BMI) \<30kg/m2
7. varus angle degree \<10°

Exclusion Criteria:

1. advanced case of TFOA (G VI KL scale), which requires total knee replacement.
2. flexion deformity ≥15°
3. inflammatory disease (such as rheumatoid arthritis).

Where it's running

  • Faculty of medicine, Sohag university
    Sohag, Sohag Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.