Management approaches for odontogenic keratocysts
Analysis of Odontogenic Keratocyst Treated With Various Modalities Over a 10-year
NA · Qassim University · NCT06133764
This study tests different surgical methods for treating odontogenic keratocysts to see which one works best at preventing them from coming back.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 10 Years and up |
| Sex | All |
| Sponsor | Qassim University (other) |
| Locations | 1 site (Buraydah, Qassim Region) |
| Trial ID | NCT06133764 on ClinicalTrials.gov |
What this trial studies
This study evaluates various surgical management techniques for odontogenic keratocysts, including decompression/marsupialization, enucleation, and combinations with chemical cauterization and peripheral ostectomy. The goal is to determine the most effective approach to minimize recurrence rates of these cysts. Participants will be followed for a period of 10 years to assess outcomes such as total resolution, partial resolution, and recurrence. The study aims to clarify the best practices in managing this contentious pathological phenomenon in the maxillofacial region.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with odontogenic keratocysts who are undergoing one of the specified surgical treatments.
Not a fit: Patients who have undergone resection or have cyst-like lesions or neoplastic transformations will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for odontogenic keratocysts, reducing recurrence and enhancing patient outcomes.
How similar studies have performed: While there have been various approaches to managing odontogenic keratocysts, this study aims to provide a comprehensive comparison of established methods, making it a valuable addition to existing literature.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All odontogenic keratocysts that are treated by the following surgical treatment modalities: 1. Enucleation followed by peripheral ostectomy and Carnoy's solution 2. Decompression/ marsupialization 3. Enucleation 4. Enucleation and Carnoy's solution 5. Enucleation and Peripheral Ostectomy * Follow-up period 10 years Exclusion Criteria: * Cases treated with resection * Cases showed neoplastic transformation in their pathology * Cyst Like lesions
Where this trial is running
Buraydah, Qassim Region
- College of Dentistry, Qassim University — Buraydah, Qassim Region, Saudi Arabia (RECRUITING)
Study contacts
- Principal investigator: Ghada A Khalifa, Professor — College of Dentistry, Qassim University, Saudi Arabia
- Study coordinator: Ghada A Khalifa, professor
- Email: g.khalifa@qu.edu.sa
- Phone: 0069504840248
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Odontogenic Cysts, Odontogenic cysts, Odontogenic Keratocysts