Magnetic localization of sentinel nodes in oral cancer
Diagnostic Value of Sentinel Node Biopsy Guided by Magnetic Probe in Squamous Cell Oral Carcinoma: a Prospective Observational Study
This study tests a new way to find important lymph nodes in patients with early-stage oral cancer using a magnetic technique to see if it works better and causes fewer problems than traditional methods.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 24 (estimated) |
| Ages | 29 Years to 85 Years |
| Sex | All |
| Sponsor | Hospital Donostia Academic / other |
| Locations | 1 site (Donostia, Guipuzkoa) |
| Trial ID | NCT06261983 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of magnetic localization for sentinel node biopsy in patients with early-stage squamous cell oral carcinoma. By injecting superparamagnetic iron oxide near the tumor, the technique aims to accurately identify sentinel nodes with minimal complications. The study analyzes the diagnostic performance of this method in a cohort of 23 patients, achieving a high localization success rate. The findings suggest that this magnetic approach could serve as a reliable alternative to traditional methods.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with T1-T2 oral squamous cell carcinoma who have no signs of lymph node involvement.
Not a fit: Patients who have undergone previous neck surgery or are on iron chelation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could improve the accuracy of cancer staging and treatment planning for patients with oral squamous cell carcinoma.
How similar studies have performed: Other studies have shown promising results with similar magnetic localization techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Oral squamous cell carcinoma T1-T2, cN0. * Absence of alterations to iron metabolism. Exclusion Criteria: * Previous neck surgery. * Treatment with iron chelators. * Pregnant
Where this trial is running
Donostia, Guipuzkoa
- Josué Hernando Vázquez — Donostia, Guipuzkoa, Spain (Recruiting)
Study contacts
- Study coordinator: Josué Hernando, PhD, DDS
- Email: josue.hernando@gmail.com
- Phone: 0034 675825482
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.