Magnetic brain stimulation plus mirror therapy for hemispatial neglect
Official title: Evaluation of the Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect Developing After Stroke
Run by Ankara Etlik City Hospital · NCT07228871 · Data updated 2026-11-12
We will test whether adding continuous theta burst magnetic stimulation to mirror therapy helps people with hemispatial neglect after a right-sided stroke.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 22 (estimated) |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Ankara, Yenimahalle) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | January 31, 2027 |
| Study ends | January 31, 2027 |
| Registry record updated | February 24, 2026 |
| Trial ID | NCT07228871 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–75 with a first right-hemisphere ischemic or hemorrhagic stroke occurring 7 days to 1 year earlier who have hemispatial neglect and an MMSE score of 24 or higher.
✕Probably not a fit
Patients with recurrent stroke, epilepsy, metallic brain or scalp implants, significant vision or hearing problems, premorbid dementia, psychiatric or other neurological disease, or use of cognition-affecting medications are unlikely to be eligible or to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with hemispatial neglect due to a right-hemisphere ischemic or hemorrhagic stroke will be enrolled at Ankara Etlik City Hospital. Participants receive mirror therapy combined with continuous theta burst stimulation (cTBS) alongside standard cognitive rehabilitation according to the study protocol. Outcomes focus on changes in neglect severity and attention-related function over the treatment and follow-up period. Common exclusions include recurrent stroke, seizures, metal implants, significant sensory deficits, cognitive impairment, psychiatric or other neurologic disease.
Why it matters
Potential benefit: If successful, the combined treatment could reduce neglect symptoms and improve patients' ability to attend to the affected side in daily life.
How similar studies have gone: Previous trials using rTMS or mirror therapy alone have shown modest improvements in neglect, but combining cTBS with mirror therapy is less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Ischemic/haemorrhagic stroke 2. Right hemisphere lesion 3. Patients with a duration of more than 7 days but less than 1 year from the date of the event 4. Aged between 18 and 75 years 5. Patients with a Mini Mental Test Score ≥ 24 Exclusion Criteria: 1. History of recurrent stroke 2. Presence of vision or hearing problems 3. Use of medication affecting cognitive function 4. History of epilepsy 5. Pregnancy or breastfeeding 6. History of malignancy 7. Pacemaker 8. Presence of metallic implants in the brain or scalp (including cochlear implant) 9. History of premorbid dementia 10. Presence of psychiatric or additional neurological disease
Where it's running
-
Ankara Etlik City Hospital
Ankara, Yenimahalle, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Ayşe Naz Kalem Özgen, specialist
- Email: kalemnaz@gmail.com
- Phone: +90 0312 797 00 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.