Machine learning tool for managing first trimester miscarriages
Machine Learning Miscarriage Management Clinical Decision Support Tool Study
This study is testing a new computer tool to see if it can help doctors better predict how likely it is for women experiencing early miscarriages to succeed with different treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 16 Years to 55 Years |
| Sex | Female |
| Sponsor | Imperial College London Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT06384144 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop a machine learning algorithm to predict the success of expectant or medical management for first trimester miscarriages. By analyzing a retrospective cohort of approximately 1000 cases, the study will collect various clinical features such as maternal demographics, previous medical history, and ultrasound measurements. The goal is to enhance the sensitivity and specificity of the decision aid by validating the algorithm with prospective data across multiple sites. The study will take place over a minimum of three years at Queen Charlotte's and Chelsea Hospital, part of Imperial College Healthcare NHS Trust.
Who should consider this trial
Good fit: Ideal candidates include women with missed or incomplete miscarriages under 14 weeks of gestation.
Not a fit: Patients with unavailable final outcome data will not benefit from this study.
Why it matters
Potential benefit: If successful, this tool could provide personalized management options for patients experiencing first trimester miscarriages, potentially improving outcomes.
How similar studies have performed: Other studies utilizing machine learning for clinical decision support have shown promise, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Missed miscarriage and incomplete miscarriage less than 14weeks gestation * Follow-up recorded at 2 weeks Exclusion Criteria: \- Final outcome data unavailable
Where this trial is running
London
- Imperial College Heatlhcare NHS Trust — London, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.