Lung function, exercise ability, and chest muscle oxygen in smokers versus non-smokers
Official title: A Comparison of Respiratory Function, Exercise Capacity and Oxygenation Between Smokers and Non-smokers
Run by Kirsehir Ahi Evran Universitesi · NCT07027956 · Data updated 2026-11-12
This project tests whether healthy daily smokers and non-smokers differ in breathing, exercise ability, and oxygen levels in the intercostal (chest) muscles.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 42 (estimated) |
| Sponsor | Kirsehir Ahi Evran Universitesi Academic / other |
| Locations | 1 site (Kırşehir) |
| Status | Recruiting |
| Started | May 28, 2025 |
| Main results expected | September 2025 |
| Study ends | December 2025 |
| Registry record updated | June 19, 2025 |
| Trial ID | NCT07027956 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults who either smoke at least one cigarette daily for the past year or who have never smoked (or not smoked in the past year), who can walk and cooperate with testing, and who volunteer to participate.
✕Probably not a fit
People with existing cardiopulmonary disease, significant musculoskeletal problems that affect testing, or those unable to comply with test procedures are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study compares healthy adult smokers (at least one cigarette per day for the past year) with non-smokers on measures of respiratory function, exercise capacity, and intercostal muscle oxygenation. Participants undergo standardized lung function tests, a supervised exercise test to measure exercise capacity, and non-invasive measurements of chest muscle oxygenation (for example, near-infrared spectroscopy). People with known cardiopulmonary disease or musculoskeletal problems that would affect testing are excluded. The study is conducted at Kirsehir Ahi Evran University and relies on on-site physiological measurements and volunteer participation.
Why it matters
Potential benefit: If differences are found, the results could help clarify early physiological effects of smoking and support better early-warning messages or targeted interventions.
How similar studies have gone: Previous research has consistently shown reduced lung function and exercise capacity in smokers, while non-invasive intercostal muscle oxygenation measurements have been explored in smaller, less common studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria (Smokers): * According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests Inclusion Criteria (Non-smokers): * According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Non-smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests
Where it's running
-
Kirsehir Ahi Evran University
Kırşehir, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Merve Firat
- Email: mervefirat@ahievran.edu.tr
- Phone: +90 850 441 02 44
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.