Clinical trial Recruiting at 1 site Observational Ages 50 to 80

Lung cancer screening program for rural and suburban Illinois residents

Official title: Patient Identification, Prescreening and LDCT Screening for Lung Cancer With Telehealth

Run by Southern Illinois University · NCT06084078 · Data updated 2026-11-12

This project will try using a designated nurse practitioner and telehealth to help people aged 50–80 who currently smoke or quit within 15 years get low-dose CT lung cancer screening.

More Lung Cancer trials

Quick facts

Study typeObservational
Ages50 Years to 80 Years
SexAll
Enrollment10000 (estimated)
SponsorSouthern Illinois University
Academic / other
Locations1 site (Springfield, Illinois)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedAugust 31, 2029
Study endsAugust 31, 2030
Registry record updatedApril 24, 2026
Trial IDNCT06084078 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people aged 50–80 with a 20 pack-year smoking history who currently smoke or quit within the past 15 years and receive care within the participating SIU health system area.

Probably not a fit

People outside the 50–80 age range, with less than a 20 pack-year history, who quit 15 or more years ago, who cannot undergo surgery if needed, or who cannot access participating LDCT centers or telehealth are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort initiative uses electronic medical records to proactively identify people at high risk for lung cancer and contacts them by phone for eligibility confirmation and scheduling. A designated nurse practitioner (NP) will guide patients through shared decision-making, smoking-cessation counseling, and referrals, with visits conducted in person or by telehealth. Low-dose CT scans will be performed at approved centers nearer to participants' homes, and the NP will communicate results and coordinate follow-up with primary care. The program specifically aims to increase screening uptake among high-risk, racial/ethnic minority, and rural/suburban patients.

Why it matters

Potential benefit: If successful, the approach could increase screening rates and lead to earlier detection of lung cancer in high-risk rural and minority populations.

How similar studies have gone: Previous large trials have shown that LDCT screening reduces lung cancer mortality and separate navigation or telehealth programs have improved screening uptake, but combining an NP-led navigation model with telehealth specifically for rural and minority populations is less well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All individuals 50-80 years of age
* 20 pack-year smoking history
* Currently smoke or have quit within the past 15 years:

Exclusion Criteria:

* Individuals 49 years and below or 81 years and above
* Has not smoked in 15 or more years
* Individuals who develop a health problem that makes them unwilling or unable to have surgery if lung cancer is detected.

Where it's running

  • Sowmy Thuppal
    Springfield, Illinois, United States
    Recruiting

Study contacts

  • Principal investigator: Sowmy Thuppal, MD PhD — Southrn Illinois University School of Medicine
  • Study coordinator: Sowmy Thuppal, MD PhD
  • Email: sthuppal83@siumed.edu
  • Phone: 217-545-2320

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.