Lung cancer screening for high-risk Black women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot research evaluates the feasibility and acceptability of low-dose computed tomography (LDCT) screening for lung cancer specifically among U.S. Black women with a history of smoking. The study involves screening participants for eligibility, administering questionnaires, and conducting LDCT scans. It aims to address the current gap in lung cancer screening eligibility for high-risk Black women, who are often overlooked in existing guidelines. Participation is expected to last up to three months, with around 900 participants involved.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Self-identified Black individual.
* Have a self-reported history of smoking. No restriction will be placed on the number of smoking pack years participants must have nor the number of years former smokers must have quit smoking.
* Aged 50-80 years.

Exclusion Criteria:

* Individuals with a history of lung cancer.
* Individuals with symptoms suggestive of lung cancer. We will evaluate whether individuals have symptoms suggestive of lung cancer by administering an online screening questionnaire, which will ask whether they have experienced shortness of breath, whether they become easily winded, and whether they have had a chronic cough within the last 12 weeks that has not improved. Individuals who select that they have any one of these symptoms will be advised to follow up with their primary doctor and will not be eligible to participate in the study.
* Individuals with pneumonia or acute respiratory infection within 12 weeks prior to enrollment that was treated with antibiotics.

Where it's running

• University of Chicago
  Chicago, Illinois, United States Recruiting
• Massachusetts General Hospital Cancer Center
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Chi Fu Jeffrey Yang, MD — Massachusetts General Hospital
• Study coordinator: Chi Fu Jeffrey Yang, MD
• Email: cjyang@mgh.harvard.edu
• Phone: 617-724-1681

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.