Lung cancer screening for employees at Lyon Hospital

Pilot Study on Lung Cancer Screening Implementation Among Employees at Lyon Hospital

This study is testing a lung cancer screening program for hospital employees aged 50 to 75 who smoke, to see how many will participate and what influences their decision to join.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 600 (estimated)
• Ages: 50 Years to 75 Years
• Sex: All
• Sponsor: Hospices Civils de Lyon (other)
• Locations: 3 sites (Bron and 2 other locations)
• Trial ID: NCT05452200 on ClinicalTrials.gov

What this trial studies

This study aims to implement lung cancer screening among employees at Lyon Hospital to evaluate participation rates and factors influencing willingness to participate. The program targets hospital employees aged 50 to 75 who have a significant smoking history. By understanding these factors, the study seeks to improve communication and tailor screening campaigns to better reach eligible populations. The intervention includes solicitation for lung cancer screening and additional exams beyond standard procedures.

Who should consider this trial

Good fit: Ideal candidates are Lyon Hospital employees aged 50 to 75 with a significant smoking history.

Not a fit: Patients who do not work at Lyon Hospital or do not meet the smoking history criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to increased participation in lung cancer screening, potentially reducing mortality rates among high-risk individuals.

How similar studies have performed: Previous studies have shown that targeted lung cancer screening can improve participation rates, suggesting this approach may be effective.

Eligibility criteria

* Inclusion Criteria :

  * Participant have to meet the criteria below:

Lyon hospital employee at the day of inclusion:

* valid hospital employee number,
* Or retired employee for less than a year before the inclusion

AND meeting eligibility criteria as follow :

* Aged from 50 to 75 yo,
* AND smoke or have smoked ≥ 10 cigarettes/day during ≥ 30 years OR ≥ 15 cigarettes/day for at least 25 years;
* AND active smoker or smoking cessation for ≤ 15 years ;

  * Volunteer to start a program of smoking cessation if active smoker;
  * Consent form signed ;
  * Cover by health insurance.

    * Exclusion Criteria :

Participant have to NOT meet the criteria below :

* Individual not working at Lyon hospital;
* Individual not payed by the Lyon Hospital but working at it;
* Individuals not willing to participate;
* Individual working at René Sabran Hospital;
* Individual meeting one of this non eligibility for LCS criteria defined by the French recommendation:

  * Not able to climb 2 floors of stairs ;
  * Weight ≥ 140Kg
  * Underwent a chest CT scan less than 1 year ago (except screening scanner);
  * History of lung cancer of less than 5 years or under treatment ; history of any cancer under monitoring by chest scanner ;
  * Comorbidity contraindicating therapeutic options or any kind of invasive interventions ;
  * Ongoing or recent respiratory symptoms that might lead to lung cancer diagnosis (hemoptysia, weight loss, recurrent respiratory infection).
* Individual who is pregnant or breast feeding;
* Individual whose mental health is not good enough to participate;
* Individual in jail or under justice evaluation.

Where this trial is running

Bron and 2 other locations

• Hôpital L. Pradel — Bron, France (RECRUITING)
• Hôpital de la Croix Rousse - Department of Pneumology — Lyon, France (RECRUITING)
• Centre Hospitalier Lyon Sud — Pierre-Bénite, France (RECRUITING)

Study contacts

• Study coordinator: Sébastien COURAUD, Pr

Conditions: Lung Cancer, lung cancer, screening, tobacco cessation, COPD