LuAna AI help to detect problems on chest X-rays

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cluster-randomized, stepped-wedge trial compares usual physician interpretation of chest X-rays to physician interpretation assisted by LuAna, an AI diagnostic support app developed by Hospital Israelita Albert Einstein. Adults presenting with respiratory complaints who have at least one frontal chest X-ray taken at participating public health centers are included, while images from trauma, pre-operative assessment, lung cancer screening, poor-quality films, or without frontal views are excluded. Sites crossover from control to intervention according to the stepped-wedge schedule so that all clusters eventually use the AI tool, and outcomes are measured as detection rates of predefined radiographic findings such as consolidation, pleural effusion, pneumothorax, lung injury, and cardiomegaly. The trial is multicenter within the public health system and aims to validate LuAna across a diverse demographic before broader implementation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Non-reported chest X-rays (XRts) of individuals aged over 18 years.
* Individuals images with respiratory complaints.
* Chest X-rays taken during the presence of these respiratory symptoms or while being followed up for respiratory disease.
* Chest X-rays taken on any X-ray machine.
* Chest X-rays that include at least one frontal view of the chest.

Exclusion Criteria:

* Those whose chest X-ray was performed due to a history of trauma, pre-operative risk assessment, lung cancer screening, or exclusively for verifying the correct positioning of a peripheral intravenous catheter (PICC).
* Chest X-rays with technical quality below the minimum required for proper interpretation and diagnosis.
* Cases without at least one frontal view.
* X-rays printed on regular paper.

Where it's running

• FEAS Curitiba
  Curitiba, Paraná, Brazil Recruiting

Study contacts

• Principal investigator: Joselisa Paiva, PhD — Hospital Israelita Albert Einstein
• Study coordinator: Joselisa Paiva, PhD
• Email: joselisa.paiva@einstein.br
• Phone: +55 (11) 9981667340

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.