Lowering high LDL-C with personality-tailored text messages
Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages: A Three-Arm Randomized Controlled Trial
This test checks whether a single personality-tailored text message helps adults with high LDL cholesterol make and attend GP appointments more often than a general message or no message.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 3000 (estimated) |
| Ages | 21 Years to 65 Years |
| Sex | All |
| Sponsor | National University Health System, Singapore Academic / other |
| Locations | 1 site (Singapore) |
| Trial ID | NCT07415109 on ClinicalTrials.gov |
What this trial studies
This interventional program runs alongside the RESET study and enrolls RESET participants identified with high LDL-C who consented to recontact and can read English. Participants are randomized to receive either a one-time personality-tailored text message, a one-time general text message, or no message as a control, and they complete one questionnaire before and one after receiving their RESET results. The main outcome is whether participants arrange or attend a GP consultation after learning their LDL-C result. Messages are designed using temporal self-regulation theory and personalized by participant personality type to encourage prompt follow-up.
Who should consider this trial
Good fit: Ideal candidates are adults (21+) enrolled in RESET who were flagged with high LDL-C, consented to be contacted for future studies, and can read and write English.
Not a fit: People without elevated LDL-C, those unable to read or write English, or those already reliably attending GP follow-ups are unlikely to gain additional benefit.
Why it matters
Potential benefit: If successful, this approach could increase GP follow-up for people with high LDL-C, enabling earlier treatment and better cholesterol control.
How similar studies have performed: Previous research shows personality-tailored and theory-based messages can improve some health behaviors, but evidence for one-time text messages improving clinic follow-up is mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * New participants of RESET who have given consent to be contacted for future studies * ≥21 years old Exclusion Criteria: * are not able to read, write or communicate in English
Where this trial is running
Singapore
- National University of Singapore — Singapore, Singapore (Recruiting)
Study contacts
- Study coordinator: Jocelyn Chew
- Email: dbi-lab@nus.edu.sg
- Phone: +6565168687
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.