Low-sodium versus usual-salt diet after heart failure hospitalization

Evaluating Effect of Low-Sodium and Regular Diets on Heart Failure Outcomes

NA · Rutgers, The State University of New Jersey · NCT07560592

This will test whether a low-sodium (cardiac) diet lowers 30-day hospital readmissions for adults recently hospitalized with heart failure.

Quick facts

PhaseNA
Study typeInterventional
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorRutgers, The State University of New Jersey (other)
Locations1 site (New Brunswick, New Jersey)
Trial IDNCT07560592 on ClinicalTrials.gov

What this trial studies

Adults admitted with heart failure within 24 hours are assigned to either a low-sodium cardiac diet or a normal salt diet and followed for 30 days to record rehospitalizations. The trial excludes patients with markedly elevated blood pressure on admission, those on dialysis, and those in cardiogenic shock. Intake and clinical outcomes will be tracked to compare 30-day readmission rates between the two diet groups. Results aim to clarify whether sodium restriction after discharge affects short-term outcomes.

Who should consider this trial

Good fit: Adults aged over 18 who are hospitalized for heart failure and can be enrolled within 24 hours of admission are ideal candidates, provided they do not meet exclusion criteria.

Not a fit: Patients with uncontrolled hypertension on admission, end-stage renal disease requiring dialysis, or cardiogenic shock are excluded and would not receive benefit from this protocol.

Why it matters

Potential benefit: If successful, results could reduce 30-day readmissions and help shape clear dietary guidance for patients after heart failure hospitalization.

How similar studies have performed: Previous research on sodium restriction in heart failure has shown mixed results, so the question remains unsettled and further data are needed.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Above 18 years of age
* Hospitalization due to Heart Failure admitted within 24 hours

Exclusion Criteria:

* Concomitant hypertension (blood pressure \>150/90 mmHg on admission)
* End stage renal disease (on hemodialysis or peritoneal dialysis
* Cardiogenic shock

Where this trial is running

New Brunswick, New Jersey

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Heart Failure, Heart failure, Salt diet

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.