Low-load resistance training with blood flow restriction for Achilles tendon pain
Official title: Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy
Run by University of Gran Rosario · NCT05241197 · Data updated 2026-11-12
This study is testing whether low-load resistance training with blood flow restriction can help people with chronic Achilles tendon pain feel better compared to regular high-load training.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 52 (estimated) |
| Sponsor | University of Gran Rosario Academic / other |
| Locations | 1 site (Rosario, Santa Fe Province) |
| Status | Recruiting |
| Started | April 29, 2022 |
| Main results expected | November 2025 |
| Study ends | August 2026 |
| Registry record updated | December 6, 2024 |
| Trial ID | NCT05241197 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 18 to 50 with a clinical diagnosis of unilateral midportion Achilles tendinopathy lasting more than 3 months.
✕Probably not a fit
Patients with a history of ankle or foot surgery, systemic disorders, or those unable to perform the required exercises may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effects of low-load resistance training with blood flow restriction (BFR-LLT) compared to high-load training (HLT) in patients suffering from chronic midportion Achilles tendinopathy (MAT). A total of 52 participants aged 18 to 50 will be randomly assigned to either the BFR-LLT or HLT group, undergoing a 12-week rehabilitation program with assessments of pain, tendon thickness, and function at baseline, 6 weeks, and 12 weeks. The training will be conducted at the University of Gran Rosario, with evaluations performed by a blinded physiotherapist to ensure objectivity.
Why it matters
Potential benefit: If successful, this approach could provide a safer and more effective rehabilitation method for patients with Achilles tendinopathy.
How similar studies have gone: While low-load training with blood flow restriction has shown promise in other contexts, its application specifically for tendon pathology like Achilles tendinopathy is relatively novel and untested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of unilateral MAT. * Achilles pain \> 3 months. * Age ranging between 18 to 50 years, both genders. * Read and speak Spanish well enough to provide informed consent and follow study instructions. * Can attend in-clinic treatments 2-3 x weekly for the next 12 weeks. Exclusion Criteria: * Any ankle or foot surgery. * History of Achilles rupture. * Heel pain in the last 3 months. * Systemic disorders/diseases. * History of deep venous thrombosis, hypertension or blood clotting disorder. * Body mass index \> 30kg/m2. * Self-report of pregnancy. * Drug use (local steroid injection or systemic fluoroquinolones). * Pain \< 2/10 of average pain on NPRS. * VISA A score \> 90%. * Unable to perform any of the exercises of the study.
Where it's running
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University of Gran Rosario
Rosario, Santa Fe Province, Argentina Recruiting
Study contacts
- Principal investigator: Gonzalo Elias, PT — University of Gran Rosario
- Study coordinator: Gonzalo Elias, PT
- Email: gelias@ugr.edu.ar
- Phone: 543416051190
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.