Low-level laser therapy for jaw pain and muscle activity in jaw disorders

Effects of Low-Level Laser Therapy Versus Soft Occlusive Splints on Mouth Opening and Surface Electromyography in Temporomandibular Disorders

NA · Cairo University · NCT04831346

This study is testing whether low-level laser therapy can help young women with jaw pain from temporomandibular joint dysfunction feel better compared to using soft mouth splints.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 30 Years
SexFemale
SponsorCairo University (other)
Locations1 site (Giza)
Trial IDNCT04831346 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of low-level laser therapy (LLLT) compared to soft occlusive splints in treating temporomandibular joint dysfunction (TMD). It is a randomized controlled trial conducted at an outpatient university clinic, involving female participants under 30 years old with specific TMD diagnoses. Participants will be divided into three groups to assess outcomes related to pain, mouth opening, and muscle activity over a year. The study aims to provide insights into alternative treatment options for TMD.

Who should consider this trial

Good fit: Ideal candidates are females under 30 years old diagnosed with unilateral myogenous TMD and having complete permanent dentition.

Not a fit: Patients with systemic diseases, prior laser therapy experience, or those currently on specific medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could offer a non-invasive option for managing pain and improving jaw function in patients with TMD.

How similar studies have performed: Previous studies have shown promising results with low-level laser therapy for pain management, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Females less than 30 years of age, Diagnosed with unilateral myogenous TMD, Having complete permanent dentition Showing normal occlusion

Exclusion Criteria:

Prior experience of Laser therapy, Systemic diseases (rheumatoid arthritis, ankylosing spondylitis, diabetes… etc. History of trauma in the TMJ or cervical regions; Neurological disorders, Muscular diseases; Cervical pain; Bruxism, Pregnancy; Currently on medication (analgesic, anti-inflammatory, muscle relaxants or anti- depressants) Current use of dental prosthetics; Previous orthodontal treatments; or Fixed restorations affecting occlusal surfaces.

Where this trial is running

Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Temporomandibular Joint Dysfunction Syndrome, Pain, Face, Temporomandibular, Dysfunction, VAS, EMG, Laser

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.