Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Low-level laser light at different wavelengths for cervicogenic headache

Official title: Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic Headache

Run by University of Lahore · NCT07163208 · Data updated 2026-11-12

This study will try different low-level laser light wavelengths alongside standard physical therapy to see if they reduce pain and headaches in adults 18–65 with cervicogenic headache lasting at least three months.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment150 (estimated)
SponsorUniversity of Lahore
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedSeptember 5, 2024
Main results expectedSeptember 30, 2025
Study endsOctober 5, 2025
Registry record updatedSeptember 19, 2025
Trial IDNCT07163208 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 with cervicogenic headache for at least three months who have not previously received low-level laser therapy are eligible.

Probably not a fit

Patients with other primary headache disorders, prior cervical spine surgery, pregnancy or lactation, photosensitivity, or on photosensitizing medications are excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center, single-blinded randomized trial in Lahore will assign adults with cervicogenic headache to one of three LLLT wavelength groups (675 nm 30 mW, 820 nm 200 mW, or a mixed 46-cluster LED probe) with all participants also receiving routine physical therapy. Treatments are delivered three times per week for six weeks (18 sessions) using the Omega XP device, and outcomes include pain (VAS), headache frequency, cervical range of motion, neck disability (NDI), quality of life (SF-36), and forward head posture measured by camera. Participants are followed to 3 and 6 months to assess durability of effects. The trial aims to determine which wavelength option best reduces headache symptoms and improves neck function.

Why it matters

Potential benefit: If successful, the chosen wavelength could reduce headache pain and frequency and improve neck function and quality of life for people with cervicogenic headache.

How similar studies have gone: Prior LLLT studies for neck pain and cervicogenic headache have shown mixed symptom relief, but direct comparisons of specific wavelengths are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18-65 years diagnosed with cervicogenic headache based on the International Classification of Headache Disorders (ICHD-3) criteria.
* Persistent headaches for at least 3 months.
* No previous exposure to low-level laser therapy (LLLT).

Exclusion Criteria:

* Patients with other primary headache disorders (e.g., migraine, tension-type headache).
* History of cervical spine surgery.
* Pregnant or lactating women.
* Patients with a history of photosensitivity or taking photosensitizing medications.

Where it's running

  • Department of Physiotherapy, Sir Ganga Ram Hospital
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.