Low-level laser light at different wavelengths for cervicogenic headache

Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic Headache

NA · University of Lahore · NCT07163208

This study will try different low-level laser light wavelengths alongside standard physical therapy to see if they reduce pain and headaches in adults 18–65 with cervicogenic headache lasting at least three months.

Quick facts

PhaseNA
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Lahore (other)
Locations1 site (Lahore, Punjab Province)
Trial IDNCT07163208 on ClinicalTrials.gov

What this trial studies

This single-center, single-blinded randomized trial in Lahore will assign adults with cervicogenic headache to one of three LLLT wavelength groups (675 nm 30 mW, 820 nm 200 mW, or a mixed 46-cluster LED probe) with all participants also receiving routine physical therapy. Treatments are delivered three times per week for six weeks (18 sessions) using the Omega XP device, and outcomes include pain (VAS), headache frequency, cervical range of motion, neck disability (NDI), quality of life (SF-36), and forward head posture measured by camera. Participants are followed to 3 and 6 months to assess durability of effects. The trial aims to determine which wavelength option best reduces headache symptoms and improves neck function.

Who should consider this trial

Good fit: Adults aged 18–65 with cervicogenic headache for at least three months who have not previously received low-level laser therapy are eligible.

Not a fit: Patients with other primary headache disorders, prior cervical spine surgery, pregnancy or lactation, photosensitivity, or on photosensitizing medications are excluded and unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, the chosen wavelength could reduce headache pain and frequency and improve neck function and quality of life for people with cervicogenic headache.

How similar studies have performed: Prior LLLT studies for neck pain and cervicogenic headache have shown mixed symptom relief, but direct comparisons of specific wavelengths are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18-65 years diagnosed with cervicogenic headache based on the International Classification of Headache Disorders (ICHD-3) criteria.
* Persistent headaches for at least 3 months.
* No previous exposure to low-level laser therapy (LLLT).

Exclusion Criteria:

* Patients with other primary headache disorders (e.g., migraine, tension-type headache).
* History of cervical spine surgery.
* Pregnant or lactating women.
* Patients with a history of photosensitivity or taking photosensitizing medications.

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cervicogenic Headache, Low-Level Laser Therapy, Neck Pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.