Low-intensity blood flow restriction exercise for overweight and obese individuals

Effects of Low-intensity Blood Flow Restriction Exercise on Aerobic Capacity, Muscle Strength, Muscle Size, Biochemical-hormonal Parameters and Antioxidant Parameters in Overweight and Obese Individuals.

Not applicable Interventional Istanbul University · NCT06912919

This study tests if low-intensity exercise with blood flow restriction can improve health and fitness in overweight and obese young men.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages18 Years to 30 Years
SexMale
SponsorIstanbul University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06912919 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of low-intensity blood flow restriction (BFR) exercise on various health parameters in overweight and obese men aged 18-30. Participants will be randomly assigned to either a BFR-aerobic training group or a control group that performs aerobic training without BFR. The study will assess changes in aerobic capacity, muscle strength, muscle size, and biochemical-hormonal parameters, as well as antioxidant levels. Blood samples will be collected for laboratory analysis, and muscle measurements will be taken to evaluate the effectiveness of the interventions.

Who should consider this trial

Good fit: Ideal candidates are sedentary men aged 18-30 with a BMI of 25 or higher who are inactive or minimally active.

Not a fit: Patients with known cardiac or pulmonary conditions, musculoskeletal disorders, or chronic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could improve physical fitness and metabolic health in overweight and obese individuals.

How similar studies have performed: Other studies have shown promising results with blood flow restriction training, indicating potential benefits for similar populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age: 18-30 Gender: Male Body Mass Index (BMI) ≥ 25 kg/m² Inactive or minimally active individuals (assessed with the International Physical Activity Questionnaire - IPAQ) No history of metabolic, cardiovascular or neuromuscular disease Not taking any medication that affects metabolism, hormones or muscle function Able to participate in a 6-week exercise program

Exclusion Criteria:

Having a cardiac or respiratory complaint Having a known chronic disease Having a medication used regularly

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obese PatientsOverweight (BMI &gt25)ObesityBlood Flow RestrictionLow Intensity ExerciseAntioxidantMuscle Power
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.