Longterm effects of COVID-19 on health and quality of life

COVIDOM: Longterm Morbidity of SARS-CoV-2 Infection and COVID-19 Disease - Consequences for Health Status and Quality of Life (NAPKON-POP)

Observational University Hospital Schleswig-Holstein · NCT04679584

This study is trying to see how COVID-19 affects people's health and quality of life in the long run after they've been infected with the virus.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital Schleswig-Holstein Academic / other
Locations3 sites (Würzburg, Bavaria and 2 other locations)
Trial IDNCT04679584 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the longterm morbidity associated with SARS-CoV-2 infection and COVID-19 disease. It will involve a population-representative sample of individuals who have been infected with the virus, examining various organ systems to identify potential longterm health impacts. Participants will undergo detailed clinical and biochemical evaluations to understand the prevalence and consequences of these sequels on health status and quality of life. The study will also explore how behavioral changes due to the pandemic may affect overall well-being.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have had a PCR-confirmed SARS-CoV-2 infection and reside in the targeted geographic areas.

Not a fit: Patients currently experiencing acute SARS-CoV-2 infection or reinfection will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the longterm health effects of COVID-19, leading to better management and treatment strategies for affected individuals.

How similar studies have performed: Other studies have indicated potential longterm effects of COVID-19, but this study aims to provide a comprehensive population-level assessment, making it a significant contribution to the field.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PCR-confirmed SARS-CoV-2 infection
* living in one of the target areas
* age at least 18 years
* written informed consent

Exclusion Criteria:

* Acute SARS-CoV-2 infection or reinfection

Where this trial is running

Würzburg, Bavaria and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COVID-19SARS-CoV-2COVIDCoronalongterm morbidityQuality of Lifelongterm consequencesChronic impairment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.