Longitudinal study on neuropathic pain and its effects on brain function

A Multi-center Clinical Longitudinal Study of Neuropathic Pain by Collecting Data on Patients' Brain Physiology and Cognitive Function

This study is trying to see how living with neuropathic pain affects brain function and thinking over time in people who experience it.

Quick facts

• Study type: Observational
• Enrollment: 2000 (estimated)
• Ages: 18 Years to 85 Years
• Sex: All
• Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine (other)
• Locations: 1 site (Shanghai, Yangpu)
• Trial ID: NCT06290024 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect data on patients experiencing neuropathic pain by assessing various factors including brain physiology and cognitive function. Participants will undergo a series of evaluations using pain scales, cognitive assessments, and brain imaging techniques such as EEG and fNIRS. The study will track dynamic changes in these factors over time to better understand the relationship between pain and cognitive processes. By gathering comprehensive data, the study seeks to provide insights into the complexities of neuropathic pain.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 85 who have clinically diagnosed neuropathic pain with a pain score of 4 or higher.

Not a fit: Patients who do not have neuropathic pain or have participated in other drug or medical device trials within the last three months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of neuropathic pain and lead to improved management strategies for patients.

How similar studies have performed: While there have been studies on neuropathic pain, this specific approach of combining multiple assessment methods in a longitudinal design is relatively novel.

Eligibility criteria

Inclusion Criteria:

1. The subjects voluntarily participated in the study and signed an informed consent form;
2. The age is between 18 years old (inclusive) and 85 years old (inclusive), regardless of gender;
3. Body mass index (BMI) ≤ 45;
4. Clinically clearly diagnosed neuropathological pain (pain VAS score ≥4 or above);
5. Did not participate in the drug/medical device test within 3 months before the test;

Exclusion Criteria:

\-

Where this trial is running

Shanghai, Yangpu

• Ke Ma — Shanghai, Yangpu, China (RECRUITING)

Study contacts

• Study coordinator: jingting chen, phd

Conditions: Pain