Clinical trial Recruiting at 1 site Observational Ages 18 to 45 Women only

Longitudinal assessment of growth-restricted fetuses

Official title: Longitudinal Study of Intra-Uterine Growth Restriction (IUGR)

Run by University of Colorado, Denver · NCT02382601 · Data updated 2026-11-12

This study is trying to see how growth-restricted fetuses develop over time using advanced imaging to help improve care for babies born with these issues.

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Quick facts

Study typeObservational
Ages18 Years to 45 Years
SexWomen only
Enrollment200 (estimated)
SponsorUniversity of Colorado, Denver
Academic / other
Locations1 site (Aurora, Colorado)
StatusRecruiting
StartedApril 2015
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedJune 11, 2026
Trial IDNCT02382601 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are pregnant individuals whose fetuses are diagnosed with SGA based on specific ultrasound measurements.

Probably not a fit

Patients under 18 years of age or those with chromosomal anomalies identified through aneuploidy screening may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This investigation employs a longitudinal approach to study fetuses diagnosed as Small for Gestational Age (SGA) using advanced imaging techniques such as ultrasound and MRI. The study will monitor subtle physiological changes in the brain, heart, and placenta over time, correlating these findings with neurological and cardiovascular outcomes in newborns and early childhood. By assessing these changes at frequent intervals, the research aims to develop diagnostic and therapeutic templates that enhance the quality of life for infants affected by intrauterine growth restriction (IUGR).

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic practices and therapeutic strategies for infants with IUGR, enhancing their long-term health outcomes.

How similar studies have gone: Other studies have shown promise in using advanced imaging techniques to assess fetal development, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with diagnosed SGA by an ultrasound estimated fetal weight (EFW) of less than the 10th percentile or a fetal abdominal circumference of less than the 5th percentile will be included in the study at the time of their first examination.

Exclusion Criteria:

* Patients \< 18 years of age, and chromosomal anomalies as identified by regular aneuploidy screening.

Where it's running

  • University of Colorado Denver Anschutz Medical Campus
    Aurora, Colorado, United States
    Recruiting

Study contacts

  • Principal investigator: John Hobbins, MD — University of Colorado, Denver
  • Study coordinator: Emma Peek, BS
  • Email: emma.peek@cuanschutz.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.