Longitudinal assessment of growth-restricted fetuses
Official title: Longitudinal Study of Intra-Uterine Growth Restriction (IUGR)
Run by University of Colorado, Denver · NCT02382601 · Data updated 2026-11-12
This study is trying to see how growth-restricted fetuses develop over time using advanced imaging to help improve care for babies born with these issues.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Aurora, Colorado) |
| Status | Recruiting |
| Started | April 2015 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | June 11, 2026 |
| Trial ID | NCT02382601 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant individuals whose fetuses are diagnosed with SGA based on specific ultrasound measurements.
✕Probably not a fit
Patients under 18 years of age or those with chromosomal anomalies identified through aneuploidy screening may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This investigation employs a longitudinal approach to study fetuses diagnosed as Small for Gestational Age (SGA) using advanced imaging techniques such as ultrasound and MRI. The study will monitor subtle physiological changes in the brain, heart, and placenta over time, correlating these findings with neurological and cardiovascular outcomes in newborns and early childhood. By assessing these changes at frequent intervals, the research aims to develop diagnostic and therapeutic templates that enhance the quality of life for infants affected by intrauterine growth restriction (IUGR).
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic practices and therapeutic strategies for infants with IUGR, enhancing their long-term health outcomes.
How similar studies have gone: Other studies have shown promise in using advanced imaging techniques to assess fetal development, suggesting that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with diagnosed SGA by an ultrasound estimated fetal weight (EFW) of less than the 10th percentile or a fetal abdominal circumference of less than the 5th percentile will be included in the study at the time of their first examination. Exclusion Criteria: * Patients \< 18 years of age, and chromosomal anomalies as identified by regular aneuploidy screening.
Where it's running
-
University of Colorado Denver Anschutz Medical Campus
Aurora, Colorado, United States Recruiting
Study contacts
- Principal investigator: John Hobbins, MD — University of Colorado, Denver
- Study coordinator: Emma Peek, BS
- Email: emma.peek@cuanschutz.edu
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.