Longitudinal assessment of growth-restricted fetuses
Longitudinal Study of Intra-Uterine Growth Restriction (IUGR)
This study is trying to see how growth-restricted fetuses develop over time using advanced imaging to help improve care for babies born with these issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Aurora, Colorado) |
| Trial ID | NCT02382601 on ClinicalTrials.gov |
What this trial studies
This investigation employs a longitudinal approach to study fetuses diagnosed as Small for Gestational Age (SGA) using advanced imaging techniques such as ultrasound and MRI. The study will monitor subtle physiological changes in the brain, heart, and placenta over time, correlating these findings with neurological and cardiovascular outcomes in newborns and early childhood. By assessing these changes at frequent intervals, the research aims to develop diagnostic and therapeutic templates that enhance the quality of life for infants affected by intrauterine growth restriction (IUGR).
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant individuals whose fetuses are diagnosed with SGA based on specific ultrasound measurements.
Not a fit: Patients under 18 years of age or those with chromosomal anomalies identified through aneuploidy screening may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic practices and therapeutic strategies for infants with IUGR, enhancing their long-term health outcomes.
How similar studies have performed: Other studies have shown promise in using advanced imaging techniques to assess fetal development, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with diagnosed SGA by an ultrasound estimated fetal weight (EFW) of less than the 10th percentile or a fetal abdominal circumference of less than the 5th percentile will be included in the study at the time of their first examination. Exclusion Criteria: * Patients \< 18 years of age, and chromosomal anomalies as identified by regular aneuploidy screening.
Where this trial is running
Aurora, Colorado
- University of Colorado Denver Anschutz Medical Campus — Aurora, Colorado, United States (Recruiting)
Study contacts
- Principal investigator: John Hobbins, MD — University of Colorado, Denver
- Study coordinator: Emma Peek, BS
- Email: emma.peek@cuanschutz.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.