Longitudinal assessment of chemsex among young men who have sex with men

Comprehensive Assessment in a Longitudinal Study on Young Men Who Have Sex With Men Attracting to chemseX-2

Observational Institute of HIV Research and Innovation Foundation, Thailand · NCT06741306

This study looks at how young men who have sex with men use drugs during sex, what influences their choices, and how it affects their health, while also exploring the idea of a clinic to help them.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages16 Years to 35 Years
SexMale
SponsorInstitute of HIV Research and Innovation Foundation, Thailand Academic / other
Locations2 sites (Bangkok, Bangkapi and 1 other locations)
Trial IDNCT06741306 on ClinicalTrials.gov

What this trial studies

This observational study, known as CLYMAX-2, focuses on young men who have sex with men (YMSM) who engage in chemsex. It aims to assess the patterns of chemsex use, the factors influencing initiation and discontinuation, and the effects on physical and mental health. The study will also evaluate the acceptability and feasibility of developing a comprehensive chemsex clinic, as well as the effectiveness of harm reduction strategies through a prospective cohort design. Data will be collected using both qualitative and quantitative methods to provide a comprehensive understanding of the chemsex landscape among this population.

Who should consider this trial

Good fit: Ideal candidates for this study are men aged 16-35 who have sex with men and are current chemsex users.

Not a fit: Patients who do not engage in chemsex or are outside the age range may not receive any benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes and tailored services for young men who engage in chemsex.

How similar studies have performed: Other studies have shown success in similar approaches to understanding chemsex and implementing harm reduction strategies, indicating potential for positive outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Men who have sex with men
2. Aged 16-35 years
3. Current chemsex users (defined as last chemsex used within 3 months)
4. Able to read and communicate in Thai
5. Provide informed consent

Exclusion Criteria:

None

Where this trial is running

Bangkok, Bangkapi and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ChemSex Users for YMSMChemSex Users
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.