Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Long-term treatment for opioid addiction through employment

Official title: Long-Term Treatment of Opioid Use Disorder

Run by Northern Michigan University · NCT05534815 · Data updated 2026-11-12

This study tests whether giving jobs to unemployed adults with opioid addiction can help them stay drug-free and improve their work situation.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment225 (estimated)
SponsorNorthern Michigan University
Academic / other
Locations1 site (Marquette, Michigan)
StatusRecruiting
StartedMarch 1, 2023
Main results expectedFebruary 28, 2027
Study endsFebruary 29, 2028
Registry record updatedMay 2, 2025
Trial IDNCT05534815 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are unemployed and enrolled in buprenorphine or methadone maintenance treatment.

Probably not a fit

Patients who are currently incarcerated or experiencing recent hallucinations may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to address the interrelated issues of opioid addiction and unemployment by implementing a Therapeutic Workplace model. Participants will be employed and paid to work, with the requirement to provide drug-free urine samples to maintain their wages, thereby promoting drug abstinence. The study seeks to evaluate the real-world impacts of this approach, which has shown promise in previous studies for maintaining drug abstinence and improving employment outcomes. The intervention focuses on adults with opioid use disorder who are currently unemployed and receiving maintenance treatment.

Why it matters

Potential benefit: If successful, this approach could significantly improve employment rates and reduce opioid use among participants, leading to better overall health outcomes.

How similar studies have gone: Previous studies have shown success with employment-based abstinence reinforcement, making this approach promising but still requiring real-world validation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years old
* are enrolled at REACH for buprenorphine or methadone maintenance treatment
* unemployed

Exclusion Criteria:

* Applicants will be excluded if they report recent hallucinations and if they are currently a prisoner.

Where it's running

  • Northern Center for Learning and Health, Northern Michigan University, 1401 Presque Isle Ave.
    Marquette, Michigan, United States
    Recruiting

Study contacts

  • Principal investigator: Forrest Toegel, PhD — Northern Michigan University
  • Study coordinator: Forrest Toegel, PhD
  • Email: ftoegel@nmu.edu
  • Phone: 906-227-2919

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.