Long-term tracking of healthy individuals for early cancer detection
Study of Healthy Cohort for Early Detection of Cancer
This study is tracking healthy adults over 20 years to see if their lifestyle and health habits can help spot cancer early.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Trial ID | NCT05193305 on ClinicalTrials.gov |
What this trial studies
This observational study aims to follow a large cohort of healthy adults over a 20-year period to identify those who develop cancer. Participants will be adults aged 18 and older undergoing routine endoscopy, and data will be collected on their lifestyle factors, medications, and physical activity. Blood samples will also be taken to aid in the early detection of malignancies. The goal is to establish correlations between clinical and lifestyle factors and the onset of cancer, ultimately improving early diagnosis.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 and older who are undergoing routine upper or lower endoscopy.
Not a fit: Patients with current or recent history of malignancy, those unable to provide consent, or individuals with communication barriers may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection of cancer, enhancing patient outcomes and survival rates.
How similar studies have performed: Other longitudinal studies have shown promise in early cancer detection through lifestyle and clinical factor tracking, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care. Exclusion Criteria: * Persons with current malignancy * Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ. * Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires * Persons who lack the capacity to provide consent * Persons who do not speak English * Persons who are visually or hearing impaired.
Where this trial is running
Baltimore, Maryland
- Johns Hopkins Hospital — Baltimore, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Elham Afghani — Johns Hopkins University
- Study coordinator: Elham Afghani
- Email: eafghan1@jhmi.edu
- Phone: 410-955-5000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.