Long-term supervised exercise program to improve fitness and quality of life for inpatients with psychosis
Official title: Effects of a Long-term Exercise Training Program on the Functional Capacity and Health-related Quality of Life in Inpatients With Psychotic Disorders
Run by Aristotle University Of Thessaloniki · NCT07113119 · Data updated 2026-11-12
This program tries a long-term supervised exercise routine, including Pilates, to see if it improves physical function and quality of life for adults hospitalized with psychotic disorders.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Aristotle University Of Thessaloniki Academic / other |
| Locations | 1 site (Thessaloniki, Thermi) |
| Status | Recruiting |
| Started | August 4, 2024 |
| Main results expected | August 4, 2025 |
| Study ends | August 15, 2025 |
| Registry record updated | August 8, 2025 |
| Trial ID | NCT07113119 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who are inpatients with a diagnosed psychotic disorder, clinically stable and on a stable medication regimen, and willing to consent and participate in supervised exercise are the ideal candidates.
✕Probably not a fit
Participants who are clinically unstable, not on stable medication, have other primary diagnoses, are adolescents, unwilling to participate, or medically unable to exercise are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional program delivers a structured, long-duration exercise training regimen to adult inpatients diagnosed with psychotic disorders, using supervised sessions (including Pilates and other exercises) at the Sports Medicine Laboratory of Aristotle University of Thessaloniki. Participants must be clinically stable and on steady medication while enrolled, and they will be monitored throughout the intervention for safety and adherence. Outcomes focus on functional capacity, health-related quality of life, physical health markers and disability, with measurements taken before and after the program. The design responds to prior research showing benefits from shorter exercise programs by extending the intervention duration to examine longer-term effects in an inpatient population.
Why it matters
Potential benefit: If successful, the program could improve patients' physical functioning, reduce disability and cardiovascular risk, and enhance health-related quality of life.
How similar studies have gone: Shorter exercise interventions (typically 4–24 weeks) have shown benefits for physical and psychological outcomes in people with mental illness, but long-term inpatient exercise programs like this are less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * being an adult * inpatient with a diagnosis of psychotic syndrome * on stable medication * controlled as far as psychosis is concerned * consenting to participate Exclusion Criteria: * adolescents * with other diagnoses * not on stable medication * in an unstable condition * unwilling to participate in the study
Where it's running
-
Sports Medicine Laboratory, Aristotle University of Thessaloniki
Thessaloniki, Thermi, Greece Recruiting
Study contacts
- Study coordinator: Evangelia Kouidi
- Email: kouidi@phed.auth.gr
- Phone: +302310992189
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Speech-based test to estimate relapse risk in psychosis
This project will try using weekly smartphone speech recordings and short self-reports to see if an automated system can predict relapse risk in people with psychosis.
-
Changing Lives and Changing Outcomes-9 group program at Worcester Recovery Center and Hospital
This program will try a nine-session cognitive-behavioral group to help adults with serious mental illness who have current or past legal involvement increase mental health awareness and lower chances of future legal problems.
-
Deprescribing antipsychotics using multiple real patient cases
This project will see if reducing or stopping long-term antipsychotics works for adults with stable psychotic disorders by following real-world cases.
-
Cognitive Strategies in Early Psychosis 2 – how brain games and pills test decision making
This study tests whether a single dose of modafinil or d-serine, compared with placebo, changes decision making in people aged 18–35 who have recently begun experiencing psychosis.
-
iTEST: a blended mobile program to improve introspective accuracy (accurate self-judgment of abilities)
This trial tests whether iTEST — daily mobile cognitive training plus coaching that focuses on accurate self-judgment — helps adults with schizophrenia-spectrum or other psychotic disorders improve community functioning.
-
Connectivity-guided theta-burst stimulation targeting the hippocampus in schizophrenia
We will try targeted theta-burst TMS guided by brain connectivity to change hippocampus activity in adults with schizophrenia or related psychotic disorders, measuring brain signals with EEG and, for some participants, intracranial electrodes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.