Long-term outcomes of meniscal allograft transplantation

Evaluation of Clinical-functional and Radiographic Outcomes in Patients Who Underwent Meniscal Allograft Transplantation (MAT) at 10 Years.

Observational Istituto Ortopedico Rizzoli · NCT06522152

This study looks at how well meniscal allograft transplantation has worked for people who had the surgery at least 15 years ago, focusing on their knee health and quality of life now.

Quick facts

Study typeObservational
Enrollment397 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations1 site (Bologna)
Trial IDNCT06522152 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the clinical and radiographic outcomes of patients who underwent meniscal allograft transplantation at least 15 years ago. It focuses on understanding the long-term effects of this surgical intervention on knee function and the potential development of osteoarthritis. The study aims to gather data from patients aged 18 to 65 who had the procedure at the Rizzoli Orthopedic Institute, assessing their current knee health and quality of life. By analyzing these outcomes, the study seeks to provide insights into the effectiveness of meniscal transplantation over an extended period.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 18 to 65 who underwent meniscal transplantation at the Rizzoli Orthopedic Institute at least 15 years ago.

Not a fit: Patients who have not consented to participate, are unreachable, or have specific medical conditions such as infections or hematologic disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable information on the long-term benefits of meniscal allograft transplantation, potentially guiding future treatment decisions for knee disorders.

How similar studies have performed: While there have been studies on meniscal transplantation, this specific long-term evaluation is relatively novel and may provide unique insights into its effectiveness over time.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged between 18 and 65 at the time of surgery
* Both male and female
* Patients who underwent meniscal transplantation at the Rizzoli Orthopedic Institute at least 10 years ago

Exclusion Criteria:

* Patients who do not give consent to be included in the study
* Patients who are no longer reachable
* Presence of infection or hematologic, rheumatic, or coagulation disorders at the time of evaluation

Where this trial is running

Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Meniscus DisorderArthritis Knee
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.