Long-term outcomes of meniscal allograft transplantation
Official title: Evaluation of Clinical-functional and Radiographic Outcomes in Patients Who Underwent Meniscal Allograft Transplantation (MAT) at 10 Years.
Run by Istituto Ortopedico Rizzoli · NCT06522152 · Data updated 2026-11-12
This study looks at how well meniscal allograft transplantation has worked for people who had the surgery at least 15 years ago, focusing on their knee health and quality of life now.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 397 (estimated) |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 1 site (Bologna) |
| Status | Recruiting |
| Started | October 24, 2024 |
| Main results expected | July 2030 |
| Study ends | July 2030 |
| Registry record updated | October 2, 2026 |
| Trial ID | NCT06522152 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 18 to 65 who underwent meniscal transplantation at the Rizzoli Orthopedic Institute at least 15 years ago.
✕Probably not a fit
Patients who have not consented to participate, are unreachable, or have specific medical conditions such as infections or hematologic disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the clinical and radiographic outcomes of patients who underwent meniscal allograft transplantation at least 15 years ago. It focuses on understanding the long-term effects of this surgical intervention on knee function and the potential development of osteoarthritis. The study aims to gather data from patients aged 18 to 65 who had the procedure at the Rizzoli Orthopedic Institute, assessing their current knee health and quality of life. By analyzing these outcomes, the study seeks to provide insights into the effectiveness of meniscal transplantation over an extended period.
Why it matters
Potential benefit: If successful, this study could provide valuable information on the long-term benefits of meniscal allograft transplantation, potentially guiding future treatment decisions for knee disorders.
How similar studies have gone: While there have been studies on meniscal transplantation, this specific long-term evaluation is relatively novel and may provide unique insights into its effectiveness over time.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 65 at the time of surgery * Both male and female * Patients who underwent meniscal transplantation at the Rizzoli Orthopedic Institute at least 10 years ago Exclusion Criteria: * Patients who do not give consent to be included in the study * Patients who are no longer reachable * Presence of infection or hematologic, rheumatic, or coagulation disorders at the time of evaluation
Where it's running
-
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy Recruiting
Study contacts
- Study coordinator: Stefano Zaffagnini
- Email: stefano.zaffagnini@ior.it
- Phone: 0516366075
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Patient-specific 3D-printed guide versus conventional open-wedge high tibial osteotomy
This trial will test whether using patient-specific 3D-printed surgical guides makes the bone cut more accurate than the conventional technique for adults with medial knee osteoarthritis and varus deformity who are candidates for medial opening wedge high tibial osteotomy.
-
Evaluating PRP injections for knee osteoarthritis treatment
This study is testing whether platelet-rich plasma (PRP) injections can help people with knee osteoarthritis and related injuries feel better.
-
Treatment for Posteromedial Tibiofemoral Incongruence
This study is testing a new knee surgery to see if it can help people with Posteromedial Tibiofemoral Incongruence feel less pain and move better.
-
Comparing total knee replacement to robotic-assisted partial knee replacement
This study is testing whether robotic-assisted partial knee replacement helps people with severe knee arthritis recover better and feel more functional than traditional total knee replacement.
-
Arthrosamid versus steroid injections for managing knee osteoarthritis.
This trial will test whether a single Arthrosamid hydrogel injection works better than a standard steroid plus local anesthetic injection for adults with symptomatic knee osteoarthritis.
-
Platelet-rich plasma plus hyaluronic acid injections for knee osteoarthritis
We will try a single injection of platelet-rich plasma plus hyaluronic acid, platelet-rich plasma alone, or hyaluronic acid alone to see which works best for adults (40–75) with unilateral knee osteoarthritis who still have pain after conservative treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.