Long-term outcomes for patients with univentricular hearts after Fontan surgery

Prospektive Erfassung Von standardmäßig Erhobenen Daten im Rahmen Der Erlanger Fontan-Sprechstunde Zur Behandlung Und Überwachung Von PatientInnen Mit univentrikulärem Herzfehler im Sinne Einer Fontan-Zirkulation

NA · University of Erlangen-Nürnberg Medical School · NCT05563376

This study looks at how people with univentricular hearts do over the long term after Fontan surgery, focusing on their heart health, liver and kidney function, and overall well-being.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages6 Years to 60 Years
SexAll
SponsorUniversity of Erlangen-Nürnberg Medical School (other)
Locations1 site (Erlangen)
Trial IDNCT05563376 on ClinicalTrials.gov

What this trial studies

This study aims to systematically document and analyze long-term outcomes in patients who have undergone Fontan surgery for univentricular heart defects. It will investigate various factors influencing treatment outcomes, including lymphatic drainage disorders, immunological changes, and psychological and social development. The study will also assess liver and kidney health, cardiac function, and the impact of physical activity and early interventions on complications. Data will be collected through routine clinical assessments and standardized questionnaires over multiple time points.

Who should consider this trial

Good fit: Ideal candidates are individuals with congenital heart defects of the univentricular type who have undergone Fontan surgery.

Not a fit: Patients with heart conditions other than univentricular defects may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies and better long-term health outcomes for patients with univentricular hearts.

How similar studies have performed: Other studies have shown success in understanding long-term complications in similar patient populations, indicating that this approach is both relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* congenital heart defect of the univentricular type that has led to Fontan circulation

Exclusion Criteria:

* no exclusion criteria

Where this trial is running

Erlangen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Univentricular Heart

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.