Long-term observation of Eosinophilic Granulomatosis With Polyangiitis
Official title: Longitudinal Protocol for Eosinophilic Granulomatosis With Polyangiitis
Run by University of Pennsylvania · NCT00315380 · Data updated 2026-11-12
This study is trying to find new ways to track how Eosinophilic Granulomatosis With Polyangiitis affects people over time by looking at their health and collecting samples.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 700 (estimated) |
| Sponsor | University of Pennsylvania Academic / other |
| Locations | 15 sites (San Diego, California and 14 other locations) |
| Status | Recruiting |
| Started | April 2006 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | August 28, 2026 |
| Trial ID | NCT00315380 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with Eosinophilic Granulomatosis With Polyangiitis.
✕Probably not a fit
Patients who are unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on Eosinophilic Granulomatosis With Polyangiitis (EGPA), a rare immune disorder characterized by asthma, high eosinophil levels, and vasculitis. The study aims to identify new biological markers that can help assess disease activity and severity in patients with EGPA. Participants will undergo regular visits every six months or annually, during which blood and urine samples will be collected, and questionnaires will be administered to evaluate their health status and disease progression. The findings may enhance clinical care and inform future drug development for EGPA.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and treatment strategies for patients with Eosinophilic Granulomatosis With Polyangiitis.
How similar studies have gone: Other studies have explored biomarkers in similar conditions, indicating potential for success in this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients with a diagnosis of eosinophilic granulomatosis with polyangiitis are eligible for the study. Parent or guardian willing to provide informed consent, if applicable Exclusion Criteria: \- Inability to give informed consent and to sign the consent form
Where it's running
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St. Joseph's Healthcare
Hamilton, Ontario, Canada Recruiting -
medius KLINIK KIRCHHEIM
Kirchheim unter Teck, Germany Recruiting -
AOU Meyer IRCCS
Florence, Italy Recruiting -
Cambridge University Hospitals Nhs Foundation Trust
Cambridge, United Kingdom Recruiting -
Imperial College Healthcare NHS Trust/ Imperial College London
London, United Kingdom Recruiting -
Guy'S and St Thomas' Nhs Foundation Trust
London, United Kingdom Recruiting
Show 9 more locations
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University of California San Diego
San Diego, California, United States Completed -
National Jewish Health
Denver, Colorado, United States Completed -
Brigham and Women's Hospital
Boston, Massachusetts, United States Completed -
Mayo Clinic
Rochester, Minnesota, United States Completed -
Cleveland Clinic Foundation
Cleveland, Ohio, United States Completed -
University of Pennsylvania
Philadelphia, Pennsylvania, United States Completed -
University of Pittsburgh
Pittsburgh, Pennsylvania, United States Completed -
University of Utah
Salt Lake City, Utah, United States Completed -
Mount Sinai Hospital
Toronto, Ontario, Canada Completed
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.