Long-term isokinetic training for knee rehabilitation
Effect and Evaluation of Long-term Isokinetic Training of Knee Joint Under the Influence of Stiffness
This study tests if a special knee training program can help people recovering from ACL injuries get stronger and move better compared to regular exercises.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT06674473 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of isokinetic rehabilitation training at optimal stiffness for patients recovering from knee injuries, specifically those with unilateral ACL ruptures. Participants will engage in a 6-week program using a portable isokinetic trainer, which is designed to maximize force exertion compared to traditional bodyweight training. The study aims to determine whether this method leads to superior improvements in muscle strength, flexibility, and overall functional recovery. Assessments will be conducted at the beginning and end of the program to measure outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 20-60 with a unilateral ACL rupture who are 3-6 months post-surgery and have no restrictions in knee movement.
Not a fit: Patients with major comorbidities, pregnant or breastfeeding women, and those unable to complete the study process may not benefit from this trial.
Why it matters
Potential benefit: If successful, this approach could enhance recovery outcomes for patients with knee injuries, leading to improved strength and flexibility.
How similar studies have performed: While similar approaches have been explored, this specific method of isokinetic training under optimal stiffness is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 20-60 years. 2. Patients with unilateral anterior cruciate ligament (ACL) rupture, with or without meniscus injury. 3. Postoperative period of 3-6 months. 4. No restriction in knee extension or flexion movements. Exclusion Criteria: 1. Patients with major diseases or conditions such as coronary heart disease, myocardial infarction, heart failure, cerebral infarction, cerebral hemorrhage, or malignant tumors. 2. Pregnant or breastfeeding women and other special populations. 3. Patients who refuse to sign the informed consent form or are unable to complete the entire study process. 4. Patients currently infected with human immunodeficiency virus (HIV), or with a history of infectious hepatitis B or C. 5. Patients with concurrent medical issues, including but not limited to: (1) Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥95 mmHg), congestive heart failure (New York Heart Association functional classification of stage III or IV). (2) Patients with mental incapacity or an inability to comprehend the study requirements.
Where this trial is running
Beijing, Beijing
- Peking University Third Hospital — Beijing, Beijing, China (Recruiting)
Study contacts
- Study coordinator: Yuanzhen Yuan, Dr.
- Email: yanggangfeng@buaa.edu.cn
- Phone: +8618811728786
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.