Long-term isokinetic training for knee rehabilitation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of isokinetic rehabilitation training at optimal stiffness for patients recovering from knee injuries, specifically those with unilateral ACL ruptures. Participants will engage in a 6-week program using a portable isokinetic trainer, which is designed to maximize force exertion compared to traditional bodyweight training. The study aims to determine whether this method leads to superior improvements in muscle strength, flexibility, and overall functional recovery. Assessments will be conducted at the beginning and end of the program to measure outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age between 20-60 years.
2. Patients with unilateral anterior cruciate ligament (ACL) rupture (with or without meniscus injury), posterior cruciate ligament (PCL) rupture, meniscal tear (M), and patellar dislocation (PD).

4\. Postoperative period of 3-6 months. 5. No restriction in knee extension or flexion movements.

Exclusion Criteria:

1. Patients with major diseases or conditions such as coronary heart disease, myocardial infarction, heart failure, cerebral infarction, cerebral hemorrhage, or malignant tumors.
2. Pregnant or breastfeeding women and other special populations.
3. Patients who refuse to sign the informed consent form or are unable to complete the entire study process.
4. Patients currently infected with human immunodeficiency virus (HIV), or with a history of infectious hepatitis B or C.
5. Patients with concurrent medical issues, including but not limited to: (1) Uncontrolled hypertension (systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥95 mmHg), congestive heart failure (New York Heart Association functional classification of stage III or IV). (2) Patients with mental incapacity or an inability to comprehend the study requirements.

Where it's running

• Peking University Third Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Yuanzhen Yuan, Dr.
• Email: yanggangfeng@buaa.edu.cn
• Phone: +8618811728786

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.