Long-term health follow-up of premature infants
A Cohort Study on the Long-term Health Outcomes of Premature Infants
This study is looking at the long-term health of preterm infants to see how their early experiences affect their growth and development over 18 years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 15 Days to 4 Months |
| Sex | All |
| Sponsor | Shanghai Children's Medical Center Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT05017389 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to establish a comprehensive database for the long-term health and development of preterm infants. It will collect clinical diagnosis, treatment, and follow-up data from approximately 1200 preterm infants admitted to the neonatal department over three years and follow them for 18 years. The study will analyze the impact of prenatal factors, postnatal treatment, and family environment on the health outcomes of these infants, including survival rates and the development of chronic diseases. The findings will help improve treatment plans and identify potential therapeutic targets.
Who should consider this trial
Good fit: Ideal candidates are live-born newborns with a gestational age of 36 weeks and 6 days or less, who are admitted to the neonatal ward within 24 hours of birth and plan to reside in Shanghai long-term.
Not a fit: Patients who have major congenital malformations or whose treatment is terminated for non-disease reasons may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly enhance the understanding and management of long-term health issues in preterm infants.
How similar studies have performed: Other studies have shown success in similar cohort approaches, indicating the potential for valuable insights into the long-term health of preterm infants.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Live born newborns with gestational age ≤ 36 + 6 weeks 2. Transfer to the neonatal ward of Shanghai Children's medical center within 24 hours after birth 3. Those who have lived in Shanghai for more than 1 year and plan to live in Shanghai for a long time. Parents voluntarily participated in the study and signed informed consent Exclusion Criteria: 1. Premature infants: termination of treatment due to family factors (non-disease reasons) and hospitalization time ≤ 2 weeks 2. Major congenital malformations 3. Parents refuse to participate in the study
Where this trial is running
Shanghai, Shanghai Municipality
- Shanghai children's medical center — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Study coordinator: Shumei Dong, master
- Email: dongshumei@scmc.com.cn
- Phone: 38626161
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.