Long-term follow-up on the prognostic value of BNP in heart failure patients with mechanical support
Official title: The Prognostic Value of proBNP in Patients Supported With Durable Mechanical Circulatory Assist Devices - a 25 Year Follow up Study.
Run by Copenhagen University Hospital, Rigshospitalet · NCT04377854 · Data updated 2026-11-12
This study is trying to see if a blood test called BNP can help predict how well heart failure patients with mechanical support will do over the long term compared to those who have had a heart transplant or are on medication.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Copenhagen University Hospital, Rigshospitalet Academic / other |
| Locations | 1 site (Copenhagen, DK) |
| Status | Recruiting |
| Started | September 18, 2020 |
| Main results expected | August 1, 2045 |
| Study ends | August 1, 2045 |
| Registry record updated | May 5, 2021 |
| Trial ID | NCT04377854 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who are referred for advanced heart failure treatment at Rigshospitalet.
✕Probably not a fit
Patients who do not provide consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the prognostic value of the biomarker BNP in patients with advanced heart failure who are receiving durable mechanical assist devices. It compares outcomes of these patients with those who have undergone heart transplantation and those who are on optimal medical therapy. The study involves a biobank where blood samples will be collected, and patients will be followed for 25 years to assess long-term outcomes. The research is conducted at the Department of Cardiology at Rigshospitalet in Denmark.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term prognostic indicators for heart failure patients receiving mechanical support.
How similar studies have gone: Other studies have shown success in using biomarkers for prognosis in heart failure, making this approach both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients referred for evaluation for advanced HF treatment at the Rigshospital in Denmark * Age\>18 years Exclusion Criteria: * No consent
Where it's running
-
Rigshospitalet
Copenhagen, Dk, Denmark Recruiting
Study contacts
- Study coordinator: Kiran Mirza, MD
- Email: KiranMirza@dadlnet.dk
- Phone: +4535451442
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.