Long-term follow-up on the prognostic value of BNP in heart failure patients with mechanical support
The Prognostic Value of proBNP in Patients Supported With Durable Mechanical Circulatory Assist Devices - a 25 Year Follow up Study.
This study is trying to see if a blood test called BNP can help predict how well heart failure patients with mechanical support will do over the long term compared to those who have had a heart transplant or are on medication.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Rigshospitalet, Denmark Academic / other |
| Locations | 1 site (Copenhagen, DK) |
| Trial ID | NCT04377854 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prognostic value of the biomarker BNP in patients with advanced heart failure who are receiving durable mechanical assist devices. It compares outcomes of these patients with those who have undergone heart transplantation and those who are on optimal medical therapy. The study involves a biobank where blood samples will be collected, and patients will be followed for 25 years to assess long-term outcomes. The research is conducted at the Department of Cardiology at Rigshospitalet in Denmark.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are referred for advanced heart failure treatment at Rigshospitalet.
Not a fit: Patients who do not provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term prognostic indicators for heart failure patients receiving mechanical support.
How similar studies have performed: Other studies have shown success in using biomarkers for prognosis in heart failure, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients referred for evaluation for advanced HF treatment at the Rigshospital in Denmark * Age\>18 years Exclusion Criteria: * No consent
Where this trial is running
Copenhagen, DK
- Rigshospitalet — Copenhagen, Dk, Denmark (Recruiting)
Study contacts
- Study coordinator: Kiran Mirza, MD
- Email: KiranMirza@dadlnet.dk
- Phone: +4535451442
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.