Clinical trial Recruiting at 1 site Observational Ages 18 and up

Long-term follow-up on the prognostic value of BNP in heart failure patients with mechanical support

Official title: The Prognostic Value of proBNP in Patients Supported With Durable Mechanical Circulatory Assist Devices - a 25 Year Follow up Study.

Run by Copenhagen University Hospital, Rigshospitalet · NCT04377854 · Data updated 2026-11-12

This study is trying to see if a blood test called BNP can help predict how well heart failure patients with mechanical support will do over the long term compared to those who have had a heart transplant or are on medication.

More Heart Failure trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorCopenhagen University Hospital, Rigshospitalet
Academic / other
Locations1 site (Copenhagen, DK)
StatusRecruiting
StartedSeptember 18, 2020
Main results expectedAugust 1, 2045
Study endsAugust 1, 2045
Registry record updatedMay 5, 2021
Trial IDNCT04377854 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who are referred for advanced heart failure treatment at Rigshospitalet.

Probably not a fit

Patients who do not provide consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the prognostic value of the biomarker BNP in patients with advanced heart failure who are receiving durable mechanical assist devices. It compares outcomes of these patients with those who have undergone heart transplantation and those who are on optimal medical therapy. The study involves a biobank where blood samples will be collected, and patients will be followed for 25 years to assess long-term outcomes. The research is conducted at the Department of Cardiology at Rigshospitalet in Denmark.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term prognostic indicators for heart failure patients receiving mechanical support.

How similar studies have gone: Other studies have shown success in using biomarkers for prognosis in heart failure, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients referred for evaluation for advanced HF treatment at the Rigshospital in Denmark
* Age\>18 years

Exclusion Criteria:

* No consent

Where it's running

  • Rigshospitalet
    Copenhagen, Dk, Denmark
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.