Long-term follow-up on AL-001 eye injection for wet macular degeneration

A Long-term Follow-up Study to Evaluate the Safety and Effectivity of AL-001 Ophthalmic Injection in Subjects with Wet Age-related Mecular Degeneration (wAMD)

Observational Beijing Anlong Biopharmaceutical Co., Ltd. · NCT06718816

This study is looking to see how safe and effective the AL-001 eye injection is for people with wet macular degeneration over a long period of time after they’ve already had it once before.

Quick facts

Study typeObservational
Enrollment21 (estimated)
Ages50 Years and up
SexAll
SponsorBeijing Anlong Biopharmaceutical Co., Ltd. Industry-sponsored
Locations1 site (Beijing, Beijing Municipality)
Trial IDNCT06718816 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the long-term safety and efficacy of AL-001 ophthalmic injection administered via suprachoroidal space in patients with wet age-related macular degeneration (wAMD). Participants must have previously received a single dose of AL-001 in an earlier clinical study. The study will involve regular follow-up visits to monitor the outcomes and any potential side effects associated with the treatment. The focus is on gathering data to better understand the long-term effects of this innovative injection method.

Who should consider this trial

Good fit: Ideal candidates are individuals who have previously participated in a study involving AL-001 and received the injection.

Not a fit: Patients who have not previously received AL-001 or those who do not meet the inclusion criteria will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term safety and effectiveness of AL-001 for patients suffering from wAMD.

How similar studies have performed: While this specific approach is observational, similar studies evaluating long-term effects of ophthalmic injections have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The subjects enrolled in AL-001 study and received AL-001 ophthalmic injection.
* The subject or their legal representative agrees to participate in this study and signs a written ICF.
* The subjects are willing and able to follow planned visits and procedures.

Exclusion Criteria:

* None

Where this trial is running

Beijing, Beijing Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Wet Age-related Macular Degeneration
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.