Long-term follow-up of patients with large bowel polyps after EMR treatment
Dutch National Prospective EMR Cohort. Longterm Follow Up After EMR for Large Flat/Sessile Colonic Polyps, a Prospective Study.
This study looks at how patients over 18 do after having large bowel polyps removed with a special procedure, checking for any new polyps over the next 18 months.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Radboud University Medical Center Academic / other |
| Locations | 1 site (Nijmegen, Gelderland) |
| Trial ID | NCT03545061 on ClinicalTrials.gov |
What this trial studies
This observational study aims to conduct a long-term follow-up of patients who have undergone endoscopic mucosal resection (EMR) for large flat or sessile colonic polyps. The study will track participants for 18 months post-procedure to assess outcomes and monitor for any recurrence of polyps. Eligible patients must be over 18 years old and have specific polyp characteristics as defined by the Paris classification. The study is designed to gather data that may improve future management of similar cases.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with flat or sessile colonic polyps larger than 20 mm who have undergone EMR.
Not a fit: Patients participating in competing studies, such as the CLIPPER trial, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of polyp recurrence and improve surveillance strategies for patients with large bowel polyps.
How similar studies have performed: While this study is observational and focuses on long-term outcomes, similar studies have shown success in understanding polyp management and recurrence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Flat or sessile polyp morphology (Paris classification 0-IIa/b/c, Is) * Polyp size \>20 mm * Therapy: EMR * Age \> 18 years old * Written informed consent Exclusion Criteria: * Participation in a competing study, such as the "CLIPPER trial" (registration number: NL62949.091.17).
Where this trial is running
Nijmegen, Gelderland
- Radboudumc — Nijmegen, Gelderland, Netherlands (Recruiting)
Study contacts
- Principal investigator: E. Van Geenen, dr — Radboud University Medical Center
- Study coordinator: Ayla Turan, MSc
- Email: ayla.turan@radboudumc.nl
- Phone: +31(0)611368110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.