Long-term follow-up of patients with Complex Regional Pain Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to prospectively monitor the evolution of Complex Regional Pain Syndrome (CRPS) Type I in patients, focusing on various health parameters such as quality of life, pain severity, and psychosocial factors over a two-year period. Participants will complete questionnaires to assess their symptoms, disability, and mental health, while blood samples will be collected to analyze potential biomarkers associated with CRPS. The study seeks to understand how these factors correlate with recovery and overall health status in CRPS patients.

Why it matters

Who can join: the full rules

Inclusion Criteria for patients:

* CRPS Type I (fulfilling Budapest criteria for research)
* Suffering of CRPS in a distal limb (hand or foot)
* Age \>18 years
* Pain lasting less than 6 months
* Good understanding of the French language

Inclusion criteria for control:

* Not suffering from chronic pain, including CRPS
* Age \>18 years

Exclusion Criteria for both group:

* Known or suspected non-compliance, drug or alcohol abuse,
* Inability to follow the procedures of the study, e.g. due to language problems, severe psychological disorders, dementia, etc
* For blood sample: diabetes and history of hepatitis B, C, D or HIV infection

Where it's running

• Clinique romande de réadaptation
  Sion, Valais, Switzerland Recruiting

Study contacts

• Study coordinator: michel Konzelmann, MD
• Email: michel.konzelmann@crr-suva.ch
• Phone: +41 79 314 84 84

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Neridronate extension study for CRPS-1

  This study tests IV neridronate in people with CRPS-1 who completed a previous trial, to see if it continues to help with pain and symptoms.

  Recruiting Phase 3 Ambros Therapeutics, Inc. · Phoenix, Arizona · NCT07857733

• IV neridronate for warm-type Complex Regional Pain Syndrome (CRPS-1) with a positive bone scan

  This trial will try IV neridronate to reduce pain and swelling in adults with recent-onset warm-subtype CRPS-1 who have a positive triple-phase bone scan.

  Recruiting at 33 sites Phase 3 Ambros Therapeutics, Inc. · Phoenix, Arizona and 32 other locations · NCT07210515

• Effects of whirlpool and contrast baths on pain in patients with complex regional pain syndrome after wrist fractures

  This study is testing whether whirlpool and contrast baths can help reduce pain and improve function in adults with complex regional pain syndrome after a wrist fracture.

  Recruiting Afyonkarahisar Health Sciences University · Afyonkarahisar, Afyonkarahisar · NCT06769373

• Understanding how a wrist fracture heals and why some people develop long-lasting pain

  This study tests whether genetic markers, blood signals, heart-rate patterns, and brain body maps can predict which patients will have persistent pain after a distal radius fracture.

  Recruiting Cambridge University Hospitals NHS Foundation Trust · Cambridge, Cambridgeshire · NCT07777081

• Hyperbaric oxygen therapy for severe CRPS

  This trial tests whether adding hyperbaric oxygen therapy helps people with severe complex regional pain syndrome compared with a delayed-start approach.

  Recruiting at 2 sites University Hospital Ostrava · Ostrava, Moravian-Silesian Region and 1 other locations · NCT07446712

• Effects of a high CBD cannabis extract on pain in Complex Regional Pain Syndrome

  This study is testing whether a high CBD cannabis extract can help people with Complex Regional Pain Syndrome find relief from their pain.

  Recruiting at 2 sites Phase 1 University of California, San Diego · La Jolla, California and 1 other locations · NCT06393101

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.