Long-term follow-up of patients with Complex Regional Pain Syndrome
Longitudinal Follow-up Study About Complex Regional Pain Syndrome (CRPS). Which Are the Predictors for Return to Work and Recovery
This study is tracking how people with Complex Regional Pain Syndrome feel and function over two years to see how their pain, quality of life, and mental health change.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 110 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Clinique Romande de Readaptation Research network |
| Locations | 1 site (Sion, Valais) |
| Trial ID | NCT04703647 on ClinicalTrials.gov |
What this trial studies
This observational study aims to prospectively monitor the evolution of Complex Regional Pain Syndrome (CRPS) Type I in patients, focusing on various health parameters such as quality of life, pain severity, and psychosocial factors over a two-year period. Participants will complete questionnaires to assess their symptoms, disability, and mental health, while blood samples will be collected to analyze potential biomarkers associated with CRPS. The study seeks to understand how these factors correlate with recovery and overall health status in CRPS patients.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old with a diagnosis of CRPS Type I affecting a distal limb and experiencing pain for less than six months.
Not a fit: Patients with chronic pain conditions other than CRPS or those with severe psychological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of CRPS, potentially enhancing patient recovery and quality of life.
How similar studies have performed: While there have been studies on CRPS, this specific longitudinal approach focusing on psychosocial factors and biomarkers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria for patients: * CRPS Type I (fulfilling Budapest criteria for research) * Suffering of CRPS in a distal limb (hand or foot) * Age \>18 years * Pain lasting less than 6 months * Good understanding of the French language Inclusion criteria for control: * Not suffering from chronic pain, including CRPS * Age \>18 years Exclusion Criteria for both group: * Known or suspected non-compliance, drug or alcohol abuse, * Inability to follow the procedures of the study, e.g. due to language problems, severe psychological disorders, dementia, etc * For blood sample: diabetes and history of hepatitis B, C, D or HIV infection
Where this trial is running
Sion, Valais
- Clinique romande de réadaptation — Sion, Valais, Switzerland (Recruiting)
Study contacts
- Study coordinator: michel Konzelmann, MD
- Email: michel.konzelmann@crr-suva.ch
- Phone: +41 79 314 84 84
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.