Long-term follow-up care for stroke survivors
A Multimodal Individualized Intervention to Prevent Functional Decline After Stroke. A Randomized Controlled Trial on Long-term Follow-up After Stroke (The LAST-long Trial)
This study tests whether personalized follow-up care from a stroke coordinator can help stroke survivors maintain their independence better than standard care over 18 months.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 301 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Norwegian University of Science and Technology Academic / other |
| Locations | 4 sites (Lørenskog and 3 other locations) |
| Trial ID | NCT03859063 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a personalized, multimodal intervention aimed at preventing long-term functional decline in stroke survivors. Participants will be randomly assigned to receive either individualized follow-up care from a stroke coordinator or standard care. The intervention includes monthly assessments of physical, cognitive, and social factors, with tailored treatment plans developed to address individual needs. Patients will be monitored over 18 months, with assessments at 6, 12, and 18 months to measure outcomes such as functional independence.
Who should consider this trial
Good fit: Ideal candidates are individuals who have experienced a first-ever or recurrent stroke and are living in specific municipalities in Norway.
Not a fit: Patients with a life expectancy of less than 12 months or those with serious comorbid conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve long-term functional and cognitive outcomes for stroke survivors.
How similar studies have performed: Other studies have shown promise in using individualized interventions for stroke rehabilitation, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of first ever or recurrent stroke (ischemic stroke or hemorrhage) * mRS \< 5 * Living in Trondheim, Skedsmo or Lørenskog municipality * Less than 10 points on Short Physical Performance Battery (SPPB) OR less than 26 points on Montreal Cognitive Assessment (MoCA) OR more than 27 points on the 7 item version of the Fatigue Severity Scale (FSS-7) OR more than 7 points on the depression or anxiety items on Hospital Anxiety and Depression Scale (HADS) OR reduced hand function (i.e. fails on Motor Assessment Scale - Advanced arm- and hand function, item 3) * Able to understand Norwegian * Able and willing to sign informed consent. Exclusion Criteria: * Life expectancy \< 12 months * Other serious diseases, judged by the medical doctor to make it difficult to comply with the intervention (i.e. serious neurological diseases or drug abuse).
Where this trial is running
Lørenskog and 3 other locations
- Akershus University Hospital — Lørenskog, Norway (Recruiting)
- Vestre Viken Bærum Hospital — Sandvika, Norway (Recruiting)
- St Olavs Hospital Stroke Unit — Trondheim, Norway (Recruiting)
- Ålesund Hospital — Ålesund, Norway (Recruiting)
Study contacts
- Study coordinator: Torunn Askim, phd prof
- Email: torunn.askim@ntnu.no
- Phone: +47 73412556
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.